Isolation and identification of secondary metabolites from the aerial parts of Stachys lavandulifolia Vahl

نویسندگان

  • Fatemeh Tahmasbi Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  • Mohammad Rabbani Department of Pharmacology and Toxicology, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  • Mustafa Ghanadian Isfahan pharmaceutical sciences research center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  • Seyed Ebrahim Sajjadi Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده مقاله:

Stachys lavandulifolia Vahl is an herbaceous wild plant native to Iran which is traditionally used in Iranian folk medicine as a mild sedative tea for reducing anxiety and for treatment of gastrointestinal disorders. Our previous study on ethyl acetate extract of S. lavandulifolia proved anti-anxiolytic activity and so the present study was designed to determine chemical components of this biologically active fraction. The extract was prepared using maceration method. Column chromatography and medium pressure liquid chromatography (MPLC) was used respectively to separate the fractions. Finally some evaluated fractions were used for high pressure liquid (HPLC) and peak shaving recycle technique to achieve more purification. Separated compounds were determined using NMR analysis and mass spectroscopy. Six compounds have been isolated from ethylacetate extract of aerial parts of S. lavandulifolia including four flavonoids (apigenin, kumatakenin, penduletin and 4', 7-dihyroxy- 3, 5, 6-trimethoxy flavon), a labdan diterpenoid (labda-13-en-8, 15-diol) and an iridoid.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

isolation and identification of secondary metabolites from the aerial parts of stachys lavandulifolia vahl

stachys lavandulifolia vahl is an herbaceous wild plant native to iran which is traditionally used in iranian folk medicine as a mild sedative tea for reducing anxiety and for treatment of gastrointestinal disorders. our previous study on ethyl acetate extract of s. lavandulifolia proved anti-anxiolytic activity and so the present study was designed to determine chemical components of this biol...

متن کامل

Identification and quantitative determination of Luteolin and Apigenin in the aerial parts and an extract of Stachys lavandulifolia by HPLC

Stachys lavandulifolia is among the species that is used for immune disorders, applied topically, or taken orally as an herbal tea. The plant is also used for stomachache, anodyne, labor, and spasm. According to the results of a pharmacological survey, the extract of Stachys lavandulifolia from the aerial parts has shown to be effective in the improvement of patients suffering from anxiety diso...

متن کامل

Identification and quantitative determination of Luteolin and Apigenin in the aerial parts and an extract of Stachys lavandulifolia by HPLC

Stachys lavandulifolia is among the species that is used for immune disorders, applied topically, or taken orally as an herbal tea. The plant is also used for stomachache, anodyne, labor, and spasm. According to the results of a pharmacological survey, the extract of Stachys lavandulifolia from the aerial parts has shown to be effective in the improvement of patients suffering from anxiety diso...

متن کامل

Antibacterial activity of different extracts from the aerial parts and roots of Stachys lavandulifolia Vahl harvested at two stages of growth

Background & Aim: Nowadays, the application of traditional medicine and herbal medicinal plants instead of chemical and synthetic drugs has captured the attention of the researchers. The purpose of this study was to investigate the antimicrobial effects of the aquatic, ethanolic and methanolic (80%) extracts of the aerial and root parts of Stachys lavandulifolia Vahl which were taken f...

متن کامل

Antibacterial activity of different extracts from the aerial parts and roots of Stachys lavandulifolia Vahl harvested at two stages of growth

Background & Aim: Nowadays, the application of traditional medicine and herbal medicinal plants instead of chemical and synthetic drugs has captured the attention of the researchers. The purpose of this study was to investigate the antimicrobial effects of the aquatic, ethanolic and methanolic (80%) extracts of the aerial and root parts of Stachys lavandulifolia Vahl which were taken f...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 16  شماره Special Issue

صفحات  58- 63

تاریخ انتشار 2017-03-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023