Isolation and identification of secondary metabolites from the aerial parts of Stachys lavandulifolia Vahl
نویسندگان
چکیده مقاله:
Stachys lavandulifolia Vahl is an herbaceous wild plant native to Iran which is traditionally used in Iranian folk medicine as a mild sedative tea for reducing anxiety and for treatment of gastrointestinal disorders. Our previous study on ethyl acetate extract of S. lavandulifolia proved anti-anxiolytic activity and so the present study was designed to determine chemical components of this biologically active fraction. The extract was prepared using maceration method. Column chromatography and medium pressure liquid chromatography (MPLC) was used respectively to separate the fractions. Finally some evaluated fractions were used for high pressure liquid (HPLC) and peak shaving recycle technique to achieve more purification. Separated compounds were determined using NMR analysis and mass spectroscopy. Six compounds have been isolated from ethylacetate extract of aerial parts of S. lavandulifolia including four flavonoids (apigenin, kumatakenin, penduletin and 4', 7-dihyroxy- 3, 5, 6-trimethoxy flavon), a labdan diterpenoid (labda-13-en-8, 15-diol) and an iridoid.
منابع مشابه
isolation and identification of secondary metabolites from the aerial parts of stachys lavandulifolia vahl
stachys lavandulifolia vahl is an herbaceous wild plant native to iran which is traditionally used in iranian folk medicine as a mild sedative tea for reducing anxiety and for treatment of gastrointestinal disorders. our previous study on ethyl acetate extract of s. lavandulifolia proved anti-anxiolytic activity and so the present study was designed to determine chemical components of this biol...
متن کاملIdentification and quantitative determination of Luteolin and Apigenin in the aerial parts and an extract of Stachys lavandulifolia by HPLC
Stachys lavandulifolia is among the species that is used for immune disorders, applied topically, or taken orally as an herbal tea. The plant is also used for stomachache, anodyne, labor, and spasm. According to the results of a pharmacological survey, the extract of Stachys lavandulifolia from the aerial parts has shown to be effective in the improvement of patients suffering from anxiety diso...
متن کاملIdentification and quantitative determination of Luteolin and Apigenin in the aerial parts and an extract of Stachys lavandulifolia by HPLC
Stachys lavandulifolia is among the species that is used for immune disorders, applied topically, or taken orally as an herbal tea. The plant is also used for stomachache, anodyne, labor, and spasm. According to the results of a pharmacological survey, the extract of Stachys lavandulifolia from the aerial parts has shown to be effective in the improvement of patients suffering from anxiety diso...
متن کاملAntibacterial activity of different extracts from the aerial parts and roots of Stachys lavandulifolia Vahl harvested at two stages of growth
Background & Aim: Nowadays, the application of traditional medicine and herbal medicinal plants instead of chemical and synthetic drugs has captured the attention of the researchers. The purpose of this study was to investigate the antimicrobial effects of the aquatic, ethanolic and methanolic (80%) extracts of the aerial and root parts of Stachys lavandulifolia Vahl which were taken f...
متن کاملAntibacterial activity of different extracts from the aerial parts and roots of Stachys lavandulifolia Vahl harvested at two stages of growth
Background & Aim: Nowadays, the application of traditional medicine and herbal medicinal plants instead of chemical and synthetic drugs has captured the attention of the researchers. The purpose of this study was to investigate the antimicrobial effects of the aquatic, ethanolic and methanolic (80%) extracts of the aerial and root parts of Stachys lavandulifolia Vahl which were taken f...
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عنوان ژورنال
دوره 16 شماره Special Issue
صفحات 58- 63
تاریخ انتشار 2017-03-01
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