Investigation of NK Cell Population in Peripheral Blood and Tumor Lesions of Patients with Breast Cancer
نویسندگان
چکیده مقاله:
Background: Alteration in peripheral blood lymphocytes (PBLs) is usually investigated to provide an evidence of the host immune responses to tumor antigens. The tumor infiltrating NK cells interact most closely with the tumor cells and more accurately reflect tumor host interactions. Objective: To analyze peripheral blood and tumor associated Natural Killer (NK) cells in patients with breast cancer by immunophenotyping. Methods: Twenty women suffering from breast cancer were examined; 12 of them were confirmed histologically to be invasive ductal carcinoma. PBL and tissue samples from patients and matched control group were processed for analysis by flow cytometry. Results: Results of PBL analysis indicated a significant (P
منابع مشابه
investigation of nk cell population in peripheral blood and tumor lesions of patients with breast cancer
background: alteration in peripheral blood lymphocytes (pbls) is usually investigated to provide an evidence of the host immune responses to tumor antigens. the tumor infiltrating nk cells interact most closely with the tumor cells and more accurately reflect tumor host interactions. objective: to analyze peripheral blood and tumor associated natural killer (nk) cells in patients with breast ca...
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عنوان ژورنال
دوره 2 شماره 3
صفحات 152- 157
تاریخ انتشار 2005-09-01
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