Evaluation of Cutaneous Infections as a Result of Pseudomonas Aeruginosa and Determination of Drug Resistance Pattern in Patients of Ahwaz Hospitals

The increasing trend in the occurrence of antibiotic resistance for Pseudomonas aeruginosa (a hostile bacterium growing on skin wounds especially those as a result of burn and leading to infectious conditions) has been accompanied with numerous complications and can even lead to septicemia and mortality. The spread of skin infections, especially those as a result of resistant variants of Pseudomonas aeromonas is associated with a longer hospitalization time, higher treatment costs, and its greater spread within the office and society. In this study, samples were taken from 271 patients with usual skin infection or infections as a result of burn that were hospitalized in Golestan and Taleghani hospitals of Ahwaz. After cultivation, the isolated colonies were evaluated. Among them, the gram-negative bacilli that were oxidase-positive and unable to ferment carbohydrates were further studied. Finally, the pattern of drug resistance was obtained for Pseudomonas aeromonas through disk diffusion using Kirby-bauer method. Out of 271 studied patients, 95 (35%) had skin infection as a result of Pseudomonas aeruginosa (55 cases (77.4%)) were in the Taleghani hospital (burn accident division) and the remainder (40 cases (20%)) were in the different surgical divisions of Golestan hospital. Out of the patients, 55.8% (53) of Pseudomonas-positive cases were female and 44.2% ( 42) were male. The evaluation of antibiotic resistance pattern for isolates showed that a resistance of 100% existed for carbenicillin, cephradine, cephalexin, ceftizoxime, and cefazolin and resiatance was greater than 90% for kanamycin. The results showed that although 83% and 1000 of isolates were still sensitive to klistin and polymyxin respecttively, but because of various problems including side-effects and their deficiency in drug-stores, amikacin with a sensitivity of 51 % can still be administered as one of the most efficacious treatments for Pseudomonas infections.