Effects of Letrozole Compared with Danazol on Patients with Confirmed Endometriosis: A Randomized Clinical Trial

effects of letrozole compared with danazol on patients with confirmed endometriosis: a randomized clinical trial

background: letrozole is an aromatase inhibitor which can decrease estrogen production in peripheral tissues and endometriosis. danazol, as an androgen, inhibits estrogen production in ovaries and recently has been introduced as an aromatase inhibitor. this study was designed to compare the effects of danazol with letrozole on endometriosis symptom relief. materials and methods: this study was ...

Effects of Danazol on Clinical Improvement of Patients with Human T-cell Lymphotropic Virus Type I Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP ): A Placebo-Controlled Clinical Trial

Therapeutic Effect of Thyme (Thymus Vulgaris) Essential Oil on Patients with COVID19: A Randomized Clinical Trial

Background and Objective: SARS COV-2 is a worldwide pandemic disease. There is currently no effective cure for this virus, but some types of herbs can be a good choice for reducing its symptoms. There are some reports that Thymus Vulgaris has a high antioxidant compounds effective in strengthening the immune system, as well as anti-virus effects to reduce the respiratory symptoms. Therefore, we...

The Effect of Expressive Writing on Psychological Distress in Patients with Vitiligo: A Randomized Clinical Trial

Objective: In this clinical trial, we examined whether or not expressive writing as a psychological intervention reduces psychological distress in vitiligo patients receiving phototherapy.  Method: A total of 139 adult vitiligo patients were asked to complete the GHQ-28 in order to identify their psychiatric disturbances. The GHQ-28 scores showed that 78 patients (56.5%) had psychiatric...

Effects of additive therapy with spironolactone on albuminuria in diabetes mellitus: A pilot randomized clinical trial

Background: Early diagnosis of albuminuria and the prevention of its progression to macroalbuminuria and diabetic nephropathy are crucial. Angiotensin converting enzyme inhibitors (ACEIs) and antagonists of angiotensin II receptors type I (ARBs) are currently used as first-line treatment for albuminuria in these patients. The present study was conducted to assess the efficacy of addition of spi...

Effectiveness of Mindfulness-based Stress Reduction (MBSR) on Patients With Chronic Pain: A Randomized Clinical Trial

Objectives: This research aims to investigate the effectiveness of mindfulness-based stress reduction (MBSR) on pain intensity, anxiety, depression, and quality of life (QoL) of patients with chronic pain via randomized clinical trials. Methods: The study population consisted of all patients with chronic pain referred to Imam Reza Hospital. Of these patients, 50 cases who met the inclusion cri...