Effects of Fatty Acids, Nutrients and Vibration on Bone Mechanical Properties and its Metabolic Parameters in Rat

Purpose: The aim of this survey was to evaluate the effects of fatty acids, nutrients and vibration on bone mechanical properties and its metabolic parametr’s in rat.Materials and Methods: 56 male wistar rats weighting 150±30 were used. Rats divided into control and six experimental groups as below: Vibration, Vibration+nutrients, Vibration+nutrients+ Canola oil, Sunflower oil, Canola oil+Sunflower oil and Coconut oil. Experimental groups were treated for eight weeks with normal diet, vibration, 210 mg of Calcium, 55 IU of Vit D, 1mg of Boron and Oils amounting to %5 Of the normal diet of oils. After experimental period rats were killed and blood samples were collected, then femur and fifth lumbar vertebral bones excised.Mechanical properties of the lumbar vertebral bones and femoral neck were determined with the Axial Compression Test and Contilever Bending Test. Plasma samples were analyzed and metabolic parametrs levels were deterrnined. The data were analysed by one way ANOV A.Resalts: Mechanical properties of bones increased in the vibration group compared to those of control group. Nutrients caused significant decrease in mechanical properties of femoral neck compared to those of control group and vibration groups. Femoral neck stiffness and maximal load and Stiffness, ma-ximal load, energy to maximal load and deformation of the lumbar vertebral increased in the vibration+coconut group compared to the other groups.Conclusion: The findings showed that combination of vibration and coconut oil has beneficial effects on bone mechaninichal properties as well as metabolic parametrs especially on sex steroid hormonens.