Effects of Cypermethrin on Sexual Behaviour and Plasma Concentrations of Pituitary-Gonadal Hormones

نویسندگان

  • Ramin Hajikhani
  • Roohollah Toodeh Zaeim
چکیده مقاله:

Background Pyrethroids are commonly used as insecticides for both household and agricultural applications, and have recently been linked to endocrine disruption. Cypermethrin is a type П pyrethroid which is used widely throughout the world. The present study was aimed to investigate the effects of cypermethrin on the sexual behaviour and plasma level of pituitary-gonadal hormones of adult male mice. MaterialsAndMethods Research methodology comprised injecting mice daily with cypermethrin (10, 15, 20 mg/kg i.p.) or DMSO (0.2 ml) for five weeks. Receptive female mice were used to test male sexual behaviors (sniffing, following, mounting, and coupling). Plasma concentrations of testosterone, luteinizing hormone (LH) and follicle stimulation hormone (FSH) were measured after five weeks treatment using the ELISA method. Results The results of the present study showed that cypermethrin-treated groups exhibited reduced sexual behavior when compared with the control group. Assay results demonstrate significantly reduced serum testosterone levels (p

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effects of cypermethrin on sexual behaviour and plasma concentrations of pituitary-gonadal hormones

background: pyrethroids are commonly used as insecticides for both household and agricultural applications, and have recently been linked to endocrine disruption. cypermethrin is a type п pyrethroid which is used widely throughout the world. the present study was aimed to investigate the effects of cypermethrin on the sexual behaviour and plasma level of pituitary-gonadal hormones of adult male...

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عنوان ژورنال

دوره 4  شماره 1

صفحات  23- 28

تاریخ انتشار 2010-03-01

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