Effect of Vitamine B1 on the intensity primary dysmenorrheal

Background and Objectives: Primary Dysmenorrhea is one of the most common disorders in women affecting % 60-93 of them. This study was conducted to evaluate the therapeutic effects of Vitamin B1 on intensity of primary dysmenorrheal on students of Islamic Azad University of Hamadan in 2014. Materials and Methods: This double-blind randomized controlled trial was conducted on female students' at Islamic Azad University of Hamadan, who met the inclusion criteria. The participants were allocated randomly into two groups of intervention and control (62 participants in each group). The intervention and control groups were received vitamin B1 (100mg/day) and placebo daily during the Loteal phase (15 days) for two months, respectively. The Visual Analog Scale (VAS) was used to measure and compare pain intensity of primary dysmenorrheal before, one month and two months after the intervention in both groups. Data was analyzed using SPSS software v.16. through independent t-student test. Results: The mean score of pain was decreased in both groups after intervention and changed from 6.36&plusmn;2.24 to 3.28&plusmn;2.11 in intervention group, and from 6.66&plusmn;2.17 to 5.48&plusmn;2.03 in control group. A significant difference was found between the mean score of severity of pain before, and two month after intervention in intervention group compared to control group (P<0.001). Conclusion: According to the results of the current study using Vitamin B1, as an alternative treatment to chemical drugs, is recommended to decrease the pain intensity of primary dysmenorrheal