Effect of carvacrol on various cytokines genes expression in splenocytes of asthmatic mice
نویسندگان
چکیده مقاله:
Objective(s):With regard to pharmacological effects of carvacrol on the respiratory system, its effect on cytokines genes expression in splenocytes of asthmatic mice was examined in this study. Materials and Methods:Splenocytes were isolated from non-sensitized (control group), sensitized mice to ovalbumin (OVA) (group S), and S animals treated with dexamethasone, and three concentrations of carvacrol. IL-4, IFN-γ, TGF-β, FOXP3, and IL-17 genes expression were carried out in cultured splenocytes using the real-time PCR method. Results:Compared to the control group, IFN-γ and FOXP3 genes expression were significantly decreased (P
منابع مشابه
effect of carvacrol on various cytokines genes expression in splenocytes of asthmatic mice
objective(s):with regard to pharmacological effects of carvacrol on the respiratory system, its effect on cytokines genes expression in splenocytes of asthmatic mice was examined in this study. materials and methods:splenocytes were isolated from non-sensitized (control group), sensitized mice to ovalbumin (ova) (group s), and s animals treated with dexamethasone, and three concentrations of ca...
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عنوان ژورنال
دوره 19 شماره 4
صفحات 402- 410
تاریخ انتشار 2016-04-01
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