Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis

نویسندگان

  • Askari , Asra Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
  • Bijeh , Nahid Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
  • Rashid Lamir , Amir Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
  • Momeni Moghadam , Majid Department of Biology, Faculty of Basic Sciences, Hakim Sabzevari University, Sabzevar, Iran
چکیده مقاله:

ABSTRACT          Background and Objectives: The present study aimed to investigate effects of eight weeks of aquatic exercise and resistance training on plasma neurotrophin-4 (NT-4) levels and NT-4 expression in peripheral blood mononuclear cells (PBMCs) of women with multiple sclerosis (MS).          Methods: Thirty women with MS were randomly assigned to a resistance-training group, an aquatic exercise group and a control group. After separating plasma and PBMCs from blood samples, level of plasma NT-4 and NT-4 expression was measured after eight weeks of exercise via ELISA and Real-time PCR, respectively.         Results: The level of plasma NT-4 and NT-4 expression increased significantly following eight weeks of aquatic training and resistance training.          Conclusion: Based on the results of the present study, both resistance training and aquatic exercise can increase the level of plasma NT-4 and NT-4 expression in female MS patients. It can be concluded that such trainings could have protective and positive effects on the nervous system of MS patients.         Keywords: Exercise, Multiple Sclerosis, Neurotrophic Factors, Women.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Toll Like Receptor 2 and 4 Expression in Peripheral Blood Mononuclear Cells of Multiple Sclerosis Patients

Background: Multiple sclerosis (MS) is a T cell mediated autoimmune disease with unknown etiology. Appropriate MS therapeutic strategies need thorough understanding of both disease etiology and pathogenesis mechanisms. Ligation of TLR-2 and TLR-4 stimulates the production of several cytokines leading to CNS autoimmunity and neurodegenerative diseases. Objective: To find a relationship between M...

متن کامل

toll like receptor 2 and 4 expression in peripheral blood mononuclear cells of multiple sclerosis patients

background: multiple sclerosis (ms) is a t cell mediated autoimmune disease with unknown etiology. appropriate ms therapeutic strategies need thorough understanding of both disease etiology and pathogenesis mechanisms. ligation of tlr-2 and tlr-4 stimulates the production of several cytokines leading to cns autoimmunity and neurodegenerative diseases. objective: to find a relationship between m...

متن کامل

Effect of 8- Week Core Stability Training on some of Functional Indices in Women with Multiple Sclerosis

Introduction: Multiple Sclerosis (MS) is an autoimmune, inflammatory and chronic disease that occurs as myelin damage and destruction in the white matter of the brain, spinal cord, and optic nerves and causes functional problems in the patient. The purpose of this study was to evaluate the effect of 8- week core stability training on some of functional indices in women with multiple sclerosis. ...

متن کامل

The Effect of Eight Weeks of Aquatic Aerobic Training on ABCA1 and ABCG1 Genes Expression in the Blood Mononuclear Cells in Women After Coronary Artery Bypass Grafting

Background: The aim of this research was to investigate the effect of aquatic aerobic training on regulatory factors related to Reverse Cholesterol Transport in women after coronary artery bypass grafting (CABG). Methods: 24 middle-aged women were studied after coronary artery bypass grafting (12 were in control group and 12 in aquatic aerobic training group)....

متن کامل

Effect of 8-week resistance training on HIF-1α gene expression and Endothelial Progenitor Cells recall of blood after one session of resistance activity in elderly men

Abstract Background and Objectives Dysfunction of endothelial cells is associated with the development of atherosclerosis and cardiovascular disease. Adult endothelial progenitor cells are derived from hematopoietic stem cells capable of forming new blood vessels through a process of angiogenesis. This study was to investigate the effect of resistance training on HIF-1α gene expression and rec...

متن کامل

effect of listening strategy training on iranian efl learners listening comprehension and use of strategies

this study aimed to investigate the effects of listening strategy training on iranian efl learners listening comprehension and use of such strategies. this work, employing an experimental methodology, was conducted among 60 adult efl learners from a language institute in isfahan, iran, as participants. the participants, who were selected based on the results of a placement test, were assigned t...

15 صفحه اول

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 11  شماره 6

صفحات  1- 6

تاریخ انتشار 2017-11

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

کلمات کلیدی

کلمات کلیدی برای این مقاله ارائه نشده است

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023