Design and Synthesis of New Imidazole Derivatives of Captopril

نویسندگان

  • L Erfani Jabarian
  • MH Houshdar Tehrani
چکیده مقاله:

A new series of alkylthio imidazole analogues of captopril, an ACE inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. All the compounds thus prepared were purified and characterized by IR, NMR and Mass analytical instruments.

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design and synthesis of new imidazole derivatives of captopril

a new series of alkylthio imidazole analogues of captopril, an ace inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. all the compounds thus prepared were purified and characterized by ir, nmr and mass analytical instruments.

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عنوان ژورنال

دوره Volume 4  شماره Number 1

صفحات  37- 41

تاریخ انتشار 2010-11-20

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