Comparison of Effect of Piperine and Capsaicin with Tabata Exercise on Changes in Serum Nitric Oxide and Creatine Kinase of Kung Fu Boys

Introduction: Tabata exercise programs can produce free radicals and muscle soreness and herbal supplements may be helpful as mediators in response to oxidative damage and muscle stress. Therefore, the purpose of this study was to compare the effects of these two supplements with Tabata exercise activity on nitric oxide and creatine kinase enzyme. Methods: The research was a quasi-experimental one and the participants were boys practicing Kung Fu. Among them, 33 boys (19-25 years old) were selected as a research sample by obtaining written consent and were randomly divided into three groups: Tabata exercise, Tabata exercise + capsaicin, Tabata exercise + piperine). During the eight weeks of piperine and capsaicin supplementation, all three groups participated in a Tabata training protocol. After the last session, blood sampling was taken in two basic stages immediately.The results were compared with one-way analysis of variance and Bonferroni test in the inferential section and SPSS version 16 software. Results: Creatine kinase activity in the two groups of supplement + exercise compared to the exercise group had a significant decrease (p = 0.004) and nitric oxide (p = 0.001) in the two groups of supplement + exercise compared to the exercise group had a significant increase. These changes were more pronounced in the Tabata exercise group with capsaicin supplementation. This significance was confirmed by Bonferroni test. There was no significant difference between the two groups of Tabata exercise and capsaicin and peprin consumption. Conclusion: Both piperine and capsaicin supplements decreased creatine kinase activity and increased nitric oxide. These two supplements were able to reduce some of the oxidative damage and muscle stress resulting from exercise by different mechanisms.