BiFeO3 Magnetic Nanoparticles: A Novel, Efficient and Reusable Magnetic Catalyst for the Synthesis of Polyhydroquinoline Derivatives

Herein, it has been shown that the bismuth ferrite magnetic nanoparticles (BFO-MNPs) are new, efficient and recyclable catalysts for the synthesis of polyhydroquinoline derivatives by the Hantzsch reaction. The one-pot four-component cyclocondensation reaction of dimedone, aromatic aldehydes, ethyl acetoacetate and ammonium acetate was carried out under solvent-free conditions. The desired products were obtained in very short reaction times with high yields. The magnetic nanocatalyst was characterized by the X-Ray Diffraction (XRD) and FT-IR analysis. For the first time, the bismuth ferrite magnetic nanoparticles were used as a catalyst in the Hantzsch reaction. The catalyst was found to be reusable, which showed considerable catalytic activity after the third run.