Association of IFN-¹ Gene Polymorphism with Type 1 Diabetes in Iranian Patients
نویسندگان
چکیده مقاله:
Background: Type 1 Diabetes (T1D) is a chronic and progressive autoimmune disorder. Cytokines play a critical role in the pathogenesis of T1D. Objective: IFN-¹ polymorphism was investigated in T1D and compared with normal controls. Methods: Thirty patients suffering from T1D and 40 normal controls were studied simultaneously using PCR technique. IFN- ¹ gene was evaluated at position 5’UTR +5644. Results: There was a significant difference between patient and control groups in TT genotype (P
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عنوان ژورنال
دوره 1 شماره 2
صفحات 130- 132
تاریخ انتشار 2004-09-01
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