تاثیر رژیم غذایی حاوی عصاره هویج و گوجه فرنگی بر میزان لیپیدهای سرم موش صحرایی

Background and Aim: Study on the effect of carrot and tomato juice on the lipid metabolism in the human and experimental cases is going on. This study was performed aiming the study on the effect of short period carrot and tomato juices consumption regularly on the rat’s serum lipid level. Materials and Methods: In this experimental study, in 30 month old rats with nearly 150-200g weight divided into three groups. Serum triglyceride (TG), total cholesterol (Chol), and HDL-C concentrations were determined by a spectrophometery method using lab. For group 1 1mL tap water and TG and Chol riched mixture, for group 2 1mL carrot juice and 1mL of the same mixture and for grup3 1mL tomato juice and 1mL of mentioned mixture were given orally everyday for the period of two weeks. After two weeks nutritional intervention blood sampling was performed again and the lipids were measured. Statistical analysis was performed using t-test at P≤ 0.05 considered as a significant level. Results: Cholesterol level in group 1 (control) had a significant rising (P<0.05) after the nutritional intervention whereas in group 2 and 3 that received carrot and tomato juice Chol and TG significantly (P<0.05) decreased after the nutritional intervention. TG level in groups of control and carrotdid not change significantly (P>0.05). HDL-C level also in three groups of rats did not change significantly after the nutritional intervention. Conclusion: Carrot and tomato juices diminish Chol serum level and these effects can play a role in prevention of cardiovascular diseases.