تأثیر ده هفته تمرین سرعتی متناوب بر نشان‌گر‌های جدید کبد چرب غیر‌الکلی در زنان میان‌سال دارای اضافه وزن مبتلا به دیابت نوع 2: یک مطالعه کارآزمایی بالینی

Background and Objectives: Positive effects of sprint interval training (SIT) on weight loss and fatty liver  have been identified. The purpose of this study was to examine the effects of SIT on novel non-alchoholic fatty liver markers (fatty liver index (FLI), lipid accumulation product (LAP), hepatic steatosis index (HSI), and Framingham steatosis index (FSI)) in overweight women with type 2 diabetes. Materials & Methods: In this Clinical trial study among the patients referring to Shahrekord Hospital in the spring and summer of 2017, 35 overweight females with type 2 diabetes (aged 55.54±6.06 years, BMI= 29.64±3.48, HbA1C=9.37±87) were selected and randomaly assigned to two groups of diabetic (positive control) (n=18) and diabetic+SIT (n=17). The experimental group performed SIT for 10 weeks in a sport and health clinic. Blood samples were taken from both groups before and after 10 weeks of exercise protocols and new fatty liver indices were calculated. Dependent t-test was used for within-group comparisons and the analysis of covariance (ANCOVA) was used for between-group comparisons. Findings:  The ANCOVA results showed that 10 weeks of SIT caused a non-significant decrease in HSI (F=0.611, p=0.514), FLI (F=1.490, p=0.203) and a significant decrease in LAP (F=5.776 and p=0.009), FSI (F=4.718, p=0.034) compared to the diabetic group. Conclusion:  Regarding the results of this study, it seems that SIT is an appropriate method for the improvement of new fatty liver markers in overweight women with type 2 diabetes. Key words:  Middle-aged women, SIT, Fatty liver, Type 2 Diabetes Mellitus   Ethical approval: This protocol was registered at IRCT: IRCT20141118019995N10 at the I.R.Iran Clinical Trials Center. The Ethics Committee of the University of Shahrekord (SKU94 / 210) has approved this protocol. Funding: This article is sponsored by Shahrekord University. Conflict of interest: None declared.     How to cite this article: Banitalebi E , Mardaniyan Ghahfarrokhi M, Faramarzi M, Nasiri S. The Effect of 10 Weeks of Sprint Interval Training on New Non-Alcoholic Fatty Liver Markers in Overweight Middle-Aged Women with Type 2 Diabetes. J Rafsanjan Univ Med Sci 2018; 17 (6) : 495-510. [Farsi]