بی حسی نخاعی برای عمل جراحی سزارین: مقایسه بوپی واکا یین هیپرباریک با ایزوباریک

Aims and Background: The baricity of the solutions used for spinal anesthesia significantly affects the distribution and dissemination of local anesthetics into the spinal space. The purpose of this study was to compare the effects of hyperbaric and isobaric bupivacaine for spinal anesthesia in cesarean section. Materials and Methods: This was a randomized double blind clinical trial on sixty patients (18-40 years old) with ASA I-II, who were candidate for elective cesarean section. Spinal anesthesia was applied by isobaric bupivacaine in the first group and hyperbaric bupivacaine in the second group. The data including hemodynamic parameters of the patients, oxygen saturation level, sensory and motor block levels, and consumption of ephedrine and complications of spinal anesthesia were all recorded. Statistical analysis by using SPSS software was applied using T-test, Chi-square test, and repeated ANOVA. P values<0.05 were considered significant. Findings: Patients in both groups were almost similar regarding demographic values and the duration of surgery. Among the other recorded variables only the duration of analgesia and the frequency of nausea and vomiting was considerably higherin the isobaric group compared with the hyperbaric one (P<0.001 , P= 0.001 respectively). There was no significant difference between the two groups regarding the other variables. Conclusions: Isobaric bupivacaine had the same effectiveness as hyperbaric type for spinal anesthesia, and it even had a longer duration of analgesia. However the higher incidence of nausea and vomiting with isobaric type must be taken into account.