بررسی ویژگی‌های بالینی و اپیدمیولوژیک (فاکتورهای مربوط به میزبان) کودکان مبتلا به کالاآزار بستری شده در مرکز طبی کودکان درفاصله‌ی سال‌های 1370 تا 1382
نویسندگان
چکیده مقاله:
Background and Objectives: Kala azar is a parasitic disease which belongs to the category of metazoonoses (a communicable disease which requires at least to an invertebrate host), In Iran canines are major reservoir for it and most of patients are 6 months to 2 years old. The aim of this study was evaluation of the clinical and epidemiologic aspects of visceral leishmaniasis in patients visiting the Children Medical Center over the 12 past years. Methods: This study used the hospital records of a case series of 106 kala azar patients hospitalized in the Children's Medical Center between 1991 and 2001. We extracted and analyzed data on geographical location, background factors, clinical and laboratory findings, response to treatment and Glucantimeâ side effects. Results: The greatest number of cases was seen in 1992 and the smallest number in 1993 and 2003 the number of cases peaked in the spring. Most patients referred to the Center are aged 1 to 4 years, and there is a strong preponderance of males (82.1% vs 17.9%). The majority of these children came from families in which the breadwinner was a peasants or a laborer. Common laboratory findings included anemia, rising ESR titers and thrombocytopenia. The most striking clinical signs and symptoms were fever, splenomegaly and hepatomegaly. Eighty-three percent of the patients had shown clinical improvement, 1.9% had died and 15.1% had relapsed. Moreover, in 52.8% of cases, the disease was treated successfully with within 2 weeks the incidence of Glucantimâ side effects was low. The cities of Khorramabad, Karaj and Saveh had produced the greatest numbers of cases. Conclusions: Compared to other studies, our case series showed a higher proportion of male patients and a somewhat different clinical and laboratory profile. However, the most important achievement of this study was identification of major endemic foci in Ardabil province, northwestern parts of Ghom province, Khorramabad, and regions located south of the Alborz Mountains (e.g. Saveh
منابع مشابه
بررسی ویژگی های بالینی و اپیدمیولوژیک (فاکتورهای مربوط به میزبان) کودکان مبتلا به کالاآزار بستری شده در مرکز طبی کودکان درفاصله ی سال های ۱۳۷۰ تا ۱۳۸۲
مقدمه و اهداف: کالاآزار مدیترانه ای بیماری مشترکی بین انسان و حیوانات است که در دسته ی متازئونوزها قرار می گیرد (بیماری مشترکی که عامل آن درسیر تکاملی اش نیاز به حداقل یک میزبان بی مهره دارد). درایران سگ سانان به عنوان مخزن اصلی بیماری شناخته شده اند و اکثر بیماران را کودکان 6 ماهه تا دو ساله تشکیل می دهند. این مطالعه به منظور بررسی ویژگی های بالینی و تغییرات همه گیرشناختی (epidemiologic) بیمار...
متن کاملفاکتورهای پروگنوستیک در کودکان مبتلا به نفریت لوپوسی مرکز طبی کودکان ، 77-1368
Background: Despite several years of intensive investigation, relatively few studies have been made of children with lupus nephritis. The prognosis of children with lupus nephritis is poor for those with diffuse proliferative glomerulonephritis and active interstitial inflammation. As newer treatment modalities become available for patients with severe lupus nephritis, it become increasingly im...
متن کاملسیر بالینی، ریسک فاکتورهای عود و پیامد طولانی مدت کودکان مبتلا به سندرم نفروتیک اولیه، مرکز طبی کودکان، 79-1360
The nephrotic syndrome is the most common chronic renal disease of childhood.Materials and Methods: In this study the clinical course, risk factors for relapse and the predictors of long-term outcome of 502 patients (median age 5 years)with primary nephrotic syndrome were followed for an average of 60 months (3.5 to 240 months) from 1981 to 2000.Results: Among the 502 patients 5 (1%) achieved s...
متن کاملبررسی آلودگی به سیکلوسپوراکایتاننسیس در کودکان مبتلا به اسهال در مرکز طبی کودکان تهران 82- 1381
Background & Aim: Cyclospora cayetanensis is a new-emerging pathogenic protozoan parasite. It is a rare coccidian associated with gastrointestinal disorders. Cyclosporiasis occurs in persons of all age groups and either in immunocompetent or immunocompromised hosts. The most characteristic feature of this infection is a syndrome of acute or chronic diarrhea. This parasite is worldwide in di...
متن کاملتظاهرات بالینی و مرگ و میر در نوزادان مبتلا به سپتی سمی در مرکز طبی کودکان
Background: To identify the clinical manifestations and mortality rate among neonates with early- and late-onset sepsis.Methods: We retrospectively reviewed the hospital records in Children’s Hospital Medical Center, Tehran University of Medical Sciences of 104 neonates (50 females and 54 males) diagnosed with septicemia and treated from September 1994 to August 1995. Diagnosis of septicemia wa...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 1 شماره None
صفحات 21- 26
تاریخ انتشار 2006-02
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
کلمات کلیدی برای این مقاله ارائه نشده است
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023