بررسی اثر کلسیم سولفات در کنترل خونریزی کبدی در مدل حیوانی

Background: The control of parenchymal hemorrhage especially in liver parenchyma, despite surgical science progresses is still one of the challenges surgeons face saving the patients’ lives and there is a research challenge between the researchers in this field to introduce a more effective method. This study aimed to determine the hemostatic effect of calcium sulfate on controlling the bleeding from liver parenchymal tissue. Materials and methods: In this animal model study 60 male Wistar rats were used. A length of two cm and a depth of half a cm incision were made on each mouse’s liver and the hemostasis time was measured using calcium sulfate different concentrations (5%, 10%, 15%, 25%, and 50%) and the control method (i.e. control of bleeding by suturing). Finally, the obtained data were entered into SPSS software and analyzed using Kruskal-Wallis test and Mann-Whitney, Kolmogorov-Smirnov. Results: The hemostasis time of calcium sulfate concentration groups was significantly less than that of the control group (p<0.01). Conclusion: Calcium sulfate is an effective hemostatic agent in controlling liver parenchymal tissue hemorrhage in an animal model.