بررسی اثرات بزاق مصنوعی VA-oralube در کاهش عوارض ناشی از رادیوتراپی سروگردن

According to the direct confrontation of dentist to oral complications of patients receiving radiotherapy, this study was conducted in Cancer institute of Imam Khomeini hospital in 1376-1377. Through this study, 70 patients expecting more than 4500 CGY radiation in salivary gland area was examined for xerostomia signs and symptoms . Artificial saliva and placebo were prescribed for patients to assess the results on xerostomia. The obtained results showed VA-oralube is significantly more effective in decreasing radiation complications (mucositis, dorsal tongue surface atrophy, pain and burning sensation of mucosa, dysphagia, oral ulcers, mucosal necrosis and gingivitis) than placebo or water. Due to the other advantages of artificial saliva such as fluride content and minor side effects, it should be prescribed in patients suffering from xerostomia as it can increase their life expectancy by reducing pain and discomfort.