Azadeh Ebrahim-Habibi
Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - Bacillus Amyloliquefaciens Alpha-amylase Inhibition by Organic Solvents: A Study on Methanol, Ethanol and Propanol
Alpha-amylase is widely used as an industrial enzyme, and a therapeutic target for which inhibitors are designed. Organic solvents are used to dissolve various compounds that would be studied as moderators of alpha-amylases, but they could themselves affect enzyme activity and stability. Methanol, ethanol and propanol are simple alcohols that may be commonly used to this end, and their effect h...
[ 2 ] - Effect of Cinnamomum Verum Extract on the Amyloid Formation of Hen Egg-white Lysozyme and Study of its Possible Role in Alzheimer’s Disease
Introduction: Diagnosing and treating diseases associated with amyloid fibers remain a great challenge despite of intensive research carried out. One important approach in the development of therapeutics is the use of herbal extracts which are rich in aromatic small molecules. Cinnamomum verum extract (CE) contains proanthocyanidin and cinnamaldehyde, which have been suggested to be capab...
[ 3 ] - بررسی اثر مهارکنندگی ترکیبات شیمیایی پیشنهادی بر فعالیت آنزیم آلفا آمیلاز باکتریایی بعنوان دارویی بالقوه جهت درمان و کنترل دیابت
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[ 4 ] - مطالعه مدلسازی مولکولی و آزمایشگاهی مهارکننده‌های پیشنهادی آنزیم لیپاز
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[ 5 ] - مطالعه تاثیر فعال کننده ترکیبات پورینی بر آنزیم آلفا آمیلاز: احتمال وجود جایگاه تنظیم فعالیت در ساختار آنزیم
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[ 7 ] - The effect of Nitrochalcone on biochemical indicators and PPAR-α gene expression in nonalcoholic male NMRI mice steatosis model
Introduction: Non-alcoholic fatty liver disease (NAFLD) is associated with oxidative stress, inflammation, and decrease in peroxisome proliferator-activated receptor alpha (PPAR-α) expression. Nitrochalcone is effective ingredient of chalcones with anti-inflammatory, anti-cancer and anti-hyperglycemic properties. This study examined the effect of intraperitoneal (IP) administration of nitrochal...
[ 8 ] - Evaluating the effects of metformin on irisin and serum biochemical parameters in male sprague-dawley rats fed by a high-fat emulsion diet
Irisin is a myokine secreted mostly by muscles after exercise, and its secretion level changes in metabolic disorders. The aim of present study was to investigate the effect of metformin on changes in the levels of plasma irisin, blood glucose and insulin resistance in male Sprague-Dawley rats receiving a high-fat emulsion diet. Twenty-four rats were divided into a normal control group (n = 8) ...