Gholamreza Asadikaram
Kerman University of Medical Sciences, Kerman, Iran
[ 1 ] - In Silico Analysis of Primary Sequence and Tertiary Structure of Lepidium Draba Peroxidase
Peroxidase enzymes are vastly applicable in industry and diagnosiss. Recently, we introduced a new kind of peroxidase gene from Lepidium draba (LDP). According to protein multiple sequence alignment results, LDP had 93% similarity and 88.96% identity with horseradish peroxidase C1A (HRP C1A). In the current study we employed in silico tools to determine, to which group of peroxidase enzymes LDP...
[ 2 ] - Impact of Opium on the Serum Levels of TGF-β in Diabetic, Addicted and Addicted-Diabetic Rats
Background: Several cells of immune system such as regulatory T cells and macrophages secrete transforming growth factor-β (TGF-β) in response to different stimuli. This cytokine has inhibitory effect on immune system and diminished production of this cytokine is associated with autoimmune disorders. Objective: The aim of this study was to evaluate the influence of opium addiction on serum leve...
[ 3 ] - Mumijo Protection gainst Acetaminophen-Induced Acute Hepatic Injury: Role of Oxidative Stress
Background: A majority of people widely use acetaminophen as a sedative. Overusing the drug for prolonged periods of time can lead to acute liver damage. Mumijo, as a strong antioxidant and anti-inflammatory drug, could possibly reduce some of the acetaminophen-induced side effects on the liver. Thus, the aim of this study is to evaluate the effect of Mumijo on the liver damage...
[ 4 ] - مرگ برنامه‌ریزی شده سلول‌های بیضه در موش‌های صحرایی معتاد به تریاک
Gh.R. Asadikaram [1] , M. Asiabanha [2] , A. Rahnema [3] , Z. Shaebani Shahrbabaki [4] , M. Mahmoodi [5] , H.A. Sasan [6] Received: 12/06/2010 Sent for Revision: 27/11/2010 Received Revised Manuscript: 26/01/2011 Accepted: 03/02/2011 Background and Objectives : Apoptosis is a physiological mechanism of cell death and it can be triggered by a variety of internal and external stimuli. I...
[ 5 ] - مقایسه آنتی‌تیروئید آنتی‌بادی‌ها و میزان ید ادراری در افراد هیپوتیروئید با افراد سالم در شهرستان رفسنجان در سال 1385
Comparison of the Thyroid Autoantibodies and Urinary Iodine Concentration in Hypothyroid and Normal Individuals in Rafsanjan City in 2006 Gh.R. Asadikaram [1] , M. Torkzadeh Mahani [2] Received: 20/05/09 Sent for Revision: 21/01/10 Received Revised Manuscript: 13/10/10 Accepted: 19/10/10 Background and Objectives: Thyroid disorders are among the most prevalent autocrine diseases. ...
[ 6 ] - میزان بالای فراخوان در برنامه غربالگری کم‌کاری مادرزادی تیروئید رفسنجان
مقدمه: کم‌کاری مادرزادی تیروئید یکی از شایع‌ترین علل قابل پیش‌گیری عقب‌ماندگی ذهنی است. در این مطالعه، میزان بروز کم‌کاری مادرزادی تیروئید در رفسنجان مورد ارزیابی قرار گرفت. مواد و روش‌ها: از تمامی نوزادان متولد شده از تاریخ 1/10/1380 تا 1/2/1381 نمونه خون پاشنه پا بر روی کاغذ فیلتر مخصوص تهیه، مقادیر TSH با روش ELISA اندازه‌گیری و mIU/L 20 TSH به عنوان ملاک فراخوان در نظر گرفته شد. در هنگام ...
[ 7 ] - Extraction and Purification of Anti-Proteinase 3 (PR3) Antibodies from Egg Yolk
Recently it has been reported, that immunoglobulin Y (IgY) can be used instead of polyclonal antibodies extracted from mammals (IgG) for the purpose of diagnosis and therapy. These antibodies are found to have better properties in terms of specificity and ease of large-scale production. In addition, IgY binds neither to mammalian complement or Fc-receptors nor does it interfere with rheumatoid ...
[ 9 ] - The Effects of Opium Addiction on the Immune System Function in Patients with Fungal Infection
Background: The use of narcotics such as opium exposes addicts as susceptible targets of different diseases so that they might easily be exposed to different diseases such as fungal infections. The present study aimed to investigate the effects of addiction to opium and fungal infection on plasma levels of certain cytokines including interleukin-4 (IL-4), IL-6, IL-17, Interferon gamma (IFN-γ) a...
[ 10 ] - Effect of shilajit on the levels of pro-inflammatory and anti inflammatory cytokines in ulcerative colitis induced by acetic acid in male rats
Background: The levels of IL-13, IL-4, IL-1B, TNF-α and IL-10 alter in the colon of people with ulcerative colitis. previous studies, it was found that shilajit (asphaltum) was effective in the improvement of ulcerative colitis.we guessed that the shilajit has been able to improve the ulcerative colitis by affecting the amount of cytokines. Objective: The aim of the present study was to investi...
[ 11 ] - Caring Behaviors Related to COVID-19: A Cross-Sectional Study in the Eastern of Iran
Background: Some recommendations and health protocols were presented for controlling COVID-19 after the outbreak such as the use of face masks, observing social distance, closure of schools, and etc. Despite these protocols, we witnessed different peaks and variants of COVID-19 during more than two years.This study investigated some risky behaviors such as not wearing face masks, violating soci...
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