Majid Asadi-Shekaari
Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, I. R. Iran
[ 1 ] - Maternal feeding with walnuts (Juglans regia) improves learning and memory in their adult pups
Objective: Walnut (Juglans Regia) is a domestic fruit of Iran. Walnut kernel (WK) has many beneficial constituents such as unsaturated fatty acids, antioxidants, and vitamin E. Scientific studies have shown that fatty acids and vitamin E can modulate learning and memory processes. The aim of the present work was to study effects of walnut consumption by mothers during pregnancy and lactation on...
[ 2 ] - Gender difference in motor impairments induced by chronic administration of vinblastine
Objective(s):Neurotoxicity of anticancer drugs complicates treatment of cancer patients. Vinblastine (VBL) is reported to induce motor and cognitive impairments in patients receiving chronic low-dose regimen. Materials and Methods: The effects of VBL treatment on motor, learning and memory functions of male and female Wistar rats were studied by behavioral related tests. Animals were given chro...
[ 3 ] - The Sheep’s Urinary Bladder Matrix as a Potent Biological Materials Resource -an Ultrastructural Study
Background and Objectives: Biological scaffold resources composed of extracellular matrix (ECM) have been shown to make easy the practical remodeling of various tissues in both animal and human studies. The goal of current study was to make sheet form of ECM from sheep’s urinary bladder. Methods: ECM was extracted from Sheep’s urinary bladder according to standard method. Scanning electron ...
[ 4 ] - بررسی اثرات حفاظتی مغز گردو بر مرگ نورونی و واکنش آستروسیت‌ها متعاقب انسداد سرخ رگ مغزی میانی در موش صحرائی نر
سابقه و هدف: سکته مغزی یک علت اصلی مرگ و میر و ناتوانی در بسیاری از کشورهاست. هیچ درمان قطعی برای این بیماری وجود ندارد، لذا جستجو برای یافتن مواد حفاظت کننده نورونی با حداقل اثرات مضر بایستی ادامه یابد. محصولات طبیعی احتمالا" منبع ایده آلی برای یافتن عوامل سالم و ارزشمند در زمینه درمان سکته مغزی می باشند. مغز گردو حاوی مواد مفید فراوان با خواص آنتی اکسیدانی و ضد التهابی است. هدف مطالعه حاضر بر...
[ 5 ] - Nepeta Dschuparensis Bornm Extract Moderates COX-2 and IL-1β Proteins in a Rat Model of Cerebral Ischemia
Background: Nepeta dschuparensis Bornm (NP) is used as a medicinal herb in Iran. In traditional medicine, this herb is extensively employed for curing ailments such as cardiovascular diseases. NP has antioxidant and anti-inflammatory properties. This project examined the effects of the NP extract on cyclooxygenase-2 (COX-2) and interleukin-1β (IL-1β) protein levels and its efficacy in neuroprot...
[ 6 ] - Hippocampal Astrocyte Response to Melatonin Following Neural Damage Induction in Rats
Introduction: Brain injury induces an almost immediate response from glial cells, especially astrocytes. Activation of astrocytes leads to the production of inflammatory cytokines and reactive oxygen species that may result in secondary neuronal damage. Melatonin is an anti-inflammatory and antioxidant agent, and it has been reported to exert neuroprotection through the prevention of neuronal d...
Co-Authors