Golnaz Vaseghi

[ 1 ] - Neuroprotective, antimicrobial, antioxidant, chemotherapeutic, and antidiabetic properties of Salvia Reuterana: A mini review

Objectives: Herbal medicine is known as a valid alternative treatment. Salvia Reuterana, which has been used in the Iranian traditional medicine, is mostly distributed in the central highlands of Iran. Salvia Reuterana is a medicinal herb with various therapeutic usages. The aim of the present review is to take account of pharmacological properties of Salvia Reuterana. Materials and Methods: Th...

[ 2 ] - The cytotoxic effect of memantine and its effect on cytoskeletal proteins expression in metastatic breast cancer cell line

Objective(s):Breast cancer is an important leading cause of death from cancer. Stathmin and tau proteins are regulators of cell motility, and their overexpression is associated with the progression and bad prognosis of breast cancer. Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is the potential inhibitor of tau protein in neurons. This study determines the effect of memantine ...

[ 3 ] - AM281, Cannabinoid Antagonist/Inverse agonist, Ameliorates Scopolamine-Induced Cognitive Deficit

Objective(s) Cannabinoids have been implicated in memory deficit. We examined the effect of AM281, cannabinoid antagonist/inverse agonist in prevention of scopolamine-induced cognitive deficit. Materials and Methods Object recognition task was used to evaluate memory in mice. Exploration time in the first and the second trial was recorded. The differences in exploration between a previously...

[ 4 ] - Standardized Punica Granatum Pericarp Extract, Suppresses Tumor Proliferation and Angiogenesis in a Mouse Model of Melanoma: Possible Involvement of PPARα and PPARγ Pathways

Melanoma is a challenging disease to treat. Punica granatum L. has a potential anticancer effect. This study determined the antiproliferative and antiangiogenic potential of the extract from pomegranate peel (PPE) in melanoma. Melanoma cells (1 × 106) were injected to C57BL6 mice subcutaneously. On 8th day, mice were randomly divided into 9 groups. Group 1 was considered as control and received...

[ 5 ] - Standardized Punica Granatum Pericarp Extract, Suppresses Tumor Proliferation and Angiogenesis in a Mouse Model of Melanoma: Possible Involvement of PPARα and PPARγ Pathways

Melanoma is a challenging disease to treat. Punica granatum L. has a potential anticancer effect. This study determined the antiproliferative and antiangiogenic potential of the extract from pomegranate peel (PPE) in melanoma. Melanoma cells (1 × 106) were injected to C57BL6 mice subcutaneously. On 8th day, mice were randomly divided into 9 groups. Group 1 was considered as control and received...

[ 6 ] - Evaluation of the Anti-tuberculosis and Cytotoxic Potential of the Seaweed Padina australis

Background: Marine seaweeds synthesize different types of compounds with various biological activities, including anti-tuberculosis and anticancer effects. Objective: The aim of this study was to evaluate anti tuberculosis of Padina australis and cytotoxicity of different fractions of this seaweed. Methods: Padina australis was collected from coasts of Persian Gulf, identified and e...

[ 7 ] - Measurement of pyruvate dehydrogenase enzyme in patients with diffuse large B-cell lymphoma relapse

Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma (NHL), which is the most common type of lymphoma. NHL comprises a group of clinically and biologically diverse diseases, which range from indolent to aggressive clinical courses. Despite treatment advances in the last three decades with the use of combination immunotherapy, a significant fraction...

[ 8 ] - Comparing the Effects of 4 and 12 Weeks of Aerobic Training on Tumor Volume in Female Mice with Breast Cancer

Introduction: Tumor size is a contributing factor in cancer prognosis. On the other hand, regular exercise may play an important role in inhibiting tumor growth in breast cancer. Because of the key role of tumor volume in tumor metastasis, the aim of the present study was to compare the effects of a 4-week and a 12-week aerobic training on tumor volume in female mice with breast cancer. Methods...

[ 9 ] - The Effect of Aerobic Training on Tumor Growth and Expression of Bcl-2 Gene and Protein in Female Mice with Breast Cancer

Introduction: The aim of this study was to investigate the effect of aerobic exercise with detraining in different phases of prevention on Bcl-2 gene expression and protein. Methods: For this purpose, 32 female BALB-c mice (18-20 g) were purchased and randomly assigned to four groups of primordial prevention (A), primary prevention (B), secondary prevention (C), and control (D). Group A perform...