Reza Enayati-fard

Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

[ 1 ] - Effect of Malva sylvestris cream on burn injury and wounds in rats

Objectives: Burn injury is one of the most health-threatening problems in the world. Malva sylvestris (M. sylvestris) flowershave a high mucilage content and are used as a remedy for cut wound and dermal infected wounds in Iranian folklore Medicine. The purpose of this study was to investigate the effect of M. sylvestris cream on the second degree burn injury in rats. Materials and Methods: Fiv...

[ 2 ] - Evaluation of the effect of physical variables on in vitro release of diclofenac pellets using Box-Behnken design

Objective(s): A Box-Behnken design was used for evaluation of Eudragit coated diclofenac pellets. The purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. Materials and Methods: Diclofenac was loaded onto the non-pareil beads using conventional coating pan. Film coating of pellets was done at the same pan. The effect of pla...

[ 3 ] - Correlation Between Sun Protection Factor and Antioxidant Activity, Phenol and Flavonoid Contents of Some Medicinal Plants

Long exposure of UV radiation increases risk of skin diseases such as cancer and photoallergic reactions. UV-B (280-320 nm) radiation is mainly responsible for inducing skin problems. Skin protection is a suitable method in the fight against ultraviolet radiation induced damage. Various synthetic agents have been used as photo protective but because of their potential toxicity in humans, they h...

[ 4 ] - Correlation Between Sun Protection Factor and Antioxidant Activity, Phenol and Flavonoid Contents of Some Medicinal Plants

Long exposure of UV radiation increases risk of skin diseases such as cancer and photoallergic reactions. UV-B (280-320 nm) radiation is mainly responsible for inducing skin problems. Skin protection is a suitable method in the fight against ultraviolet radiation induced damage. Various synthetic agents have been used as photo protective but because of their potential toxicity in humans, they h...

[ 5 ] - بررسی اثر دما و رطوبت بر سرعت وکینتیک رهش تئوفیلین از ماتریکس های هیدروفیل

Background and purpose: The dissolution of a drug has a major role on its bioavailability. Any change in physico-chemical properties can result in changes in drug release, and furthermore in its bioavailability. Evidence suggest that physicochemical properties of medicinal solids depend on the presence of heat and humidity. In order to overcome such changes, it is necessary to determine the sto...

[ 6 ] - تهیه و ارزیابی فراورده چشمی ژل شونده در محل دیکلوفناک سدیم

Background and purpose: In ocular delivery the physiological constraints imposed by the protective mechanisms of the eye lead to low absorption of drugs, resulting in a short duration of the therapeutic effect. Thus using in-situ gelling systems could increase the residence time of the drug in the eye. These systems are instilled as drops into the eye and undergo a sol-to-gel transition in the ...

[ 7 ] - بررسی پایداری فیزیکی حالت جامد قرص آتنولول و سازگاری آن با برخی از مواد جانبی قرص‌ها

Background and purpose: Oral route is the most frequently used route for drug administration and tablets are the most popular oral drug forms. The study of drug-excepient compatibility is an important process in development of a stable solid dosage form. Incompatibility between drugs and excipients can alter the stability and bioavailability of drugs, thereby affecting its safety and/or efficac...

[ 8 ] - بررسی پایداری فیزیکی حالت جامد و سازگاری پیروکسیکام با مواد جانبی قرص‌ها توسط روش‌های فیزیکوشیمیایی

Background and purpose: The pharmaceutical excipients can be incompatible with drug or other excipients. Thus, for each material, compatibility with formulation components and packaging materials should be examined. The dissolution of a drug has an important role in its bioavailability. Any change in the physico-chemical properties can result in changes in the drug release, and furthermore in i...

[ 9 ] - بررسی تاثیر دما و رطوبت بر خصوصیات فیزیکی و رهش Precirol کاربامازپین از پایه پلی اتیلن گلایکول و

Background and purpose: Solubility plays an important role in bioavailability of drugs. Any alter can cause changes in the physical and chemical properties of the drug release and consequently, changes in the bioavailability of the drug. It is necessary to recognize the best storage conditions to achieve desired drug release. Material and Methods: Carbamazepine tablets containing different ...

[ 10 ] - بررسی تأثیر نوع و میزان پلیمر بر پایداری فیزیکی حالت جامد و انحلال قرص‌های آهسته رهش دیلتیازم

Abstract Background and purpose: The dissolution of a drug has an important role in its bioavailability. Any change in the physico-chemical properties can result in changes in the drug release, and furthermore in its bioavailability. In order to overcome such changes, it is necessary to determine the storage conditions required for obtaining a desired drug release. Materials and methods: Di...

[ 11 ] - The effect of a topical ointment containing methanol extract of Buxus hyrcana Pojark. leaves on cutaneous wound healing in rats

Introduction: Buxus hyrcana Pojark. has been traditionally used for the treatment of skin disorders including wound injuries and recent studies have shown the therapeutic potential of some Buxus species in healing skin wounds. In this study, the effect of an ointment containing methanolic extract of B. hyrcana leaves was evaluated on the full-thickness wound healing in a rat model. Materials an...