Parisa Rezaei
Department of Pathology, Seyed-Al-Shohada Hospital, Isfahan, Iran
[ 1 ] - Evaluation of acute and sub-acute toxicity of Pinus eldarica bark extract in Wistar rats
Objective: Pinus eldarica (P. eldarica) is one of the most common pines in Iran which has various bioactive constituents and different uses in traditional medicine. Since there is no documented evidence for P. eldarica safety, the acute and sub-acute oral toxicities of hydroalcoholic extract of P. eldarica bark were investigated in male and female Wistar rats in this study. Materials and Method...
[ 2 ] - اثر سیلیمارین بر فیبروز ریوی ناشی از بلئومایسین در موش
زمینه و هدف: سیلیمارین از مواد مؤثره گیاه خار مریم (Silybum Marianum L) می‌باشد که در فیبروز کبدی از طریق مکانیسم‌های مختلفی نقش آنتی‌فیبروتیک را ایفا می‌کند. با توجه به شباهت در پاتوژنز بیماری‌های فیبروپرولیفراتیو، در این مطالعه اثر سیلیمارین بر فیبروز ریوی ناشی از بلئومایسین مورد بررسی قرار گرفت. روش بررسی: در این مطالعه تجربی فیبروز ریه در موش با تزریق منفرد داخل تراشه‌ای بلئومایسین (5/3 وا...
[ 3 ] - The Effect of Aspartate-Lysine-Isoleucine and Aspartate-Arginine-Tyrosine Mutations on the Expression and Activity of Vasopressin V2 Receptor Gene
Background: Vasopressin type 2 receptor (V2R) plays an important role in the water reabsorption in the kidney collecting ducts. V2R is a G protein coupled receptor (GPCR) and the triplet of amino acids aspartate-arginine-histidine (DRH) in this receptor might significantly influence its activity similar to other GPCR. However, the role of this motif has not been fully confirmed. Therefore, the ...
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