Maryam Mahmoudabady
Department of Physiology and Applied Physiology Research Centre, School of Medicine
[ 1 ] - Salix alba attenuated oxidative stress in the heart and kidney of hypercholesterolemic rabbits
Objective: Oxidative stress plays a critical role in the development of hypercholesterolemia-induced complications. This study evaluated the effects of aspirin and Salix alba hydroethanolic extract on oxidative stress in the heart and kidney of hypercholesterolemic rabbits. Materials and Methods: The antioxidant activity, as well as total phenolic and salicin content of S. alba (Sa) extract wer...
[ 2 ] - Nigella sativa seed decreases endothelial dysfunction in streptozotocin-induced diabetic rat aorta
Objective: Diabetes is an important risk factor for cardiovascular events. The great percent of morbidity in patients with diabetes is due to endothelial dysfunction. The present study investigated the effects of hydroalcholic extract of Nigella sativa (N. sativa) on contractile and dilatation response of isolated aorta in streptozotocin (STZ)-induced diabetic rat. Materials and Methods: Rats ...
[ 3 ] - The effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in hippocampus of STZ-induced diabetic rats
Objective: Oxidative stress plays an important role in the etiology of diabetic complications. Diabetes impairs hippocampus neurogenesis, synaptic plasticity, and learning. The aim of this study was to investigate the effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in STZ-induced diabetic rats' hippocampus. Materials and Methods: Diabetes induced by 60 mg/kg STZ, i....
[ 4 ] - Hydroalcoholic extract of Crocus sativus effects on bronchial inflammatory cells in ovalbumin sensitized rats
Objective: Inflammation is one of the major components of asthma. Our aim was to evaluate the effects of C. sativus extract on total and differential white blood cells (WBC) count in lung lavage fluid (LLF) of ovalbumin-sensitized rats. Materials and Methods: Forty rats were divided into five groups (n = 8 for each group) as control (C), sensitized with injection and inhalation of ovalbumin (OA...
[ 5 ] - Preventive effects of hydroalcoholic extract of saffron on hematological parameters of experimental asthmatic rats
Objective: Asthma is a chronic inflammatory disease of the respiratory airways distinguished by edema and infiltration of inflammatory immune cells. To test our hypothesis about the anti-inflammatory effect of saffron, we examined effects of Crocus sativus (C. sativus) extract as a prophylactic anti-inflammatory agent in sensitized rats. Materials and Methods: To induce experimental asthma, rat...
[ 6 ] - مقایسه اثر عصاره آبی– الکلی تخم سیاهدانه و متفورمین بر پارامترهای بیوشیمیایی خون در موش‌های صحرایی دیابتی‌شده با استرپتوزوتوسین
اهداف: بیماری دیابت با افزایش سطح قندخون ناشی از فقدان انسولین یا مقاومت بافت‌های محیطی به انسولین و یا هر دو همراه است. هدف از این مطالعه، بررسی اثرات عصاره آبی- الکلی تخم سیاهدانه بر پارامترهای بیوشیمیایی خون در موش‌های صحرایی نر دیابتی‌شده با استرپتوزوتوسین بود. مواد و روش ها: این مطالعه مداخله‌ای با استفاده از 60 سر موش صحرایی نر انجام شد. حیوانات به‌طور تصادفی به 6 گروه 10تایی کنتر...
[ 7 ] - The effects of cinnamon on risk factors of cardiovascular disease
Introduction: Herbal medicine is being considered today due to the side effects and high prices of chemical medicines. Cinnamon appears to be effective in the prevention and treatment of a variety of diseases, both as a food spice and in traditional medicine. We attempted to collect the effects of cinnamon on the occurrence of cardiovascular disorders and their related parameters in this review...