Mousa-al-reza Hajzadeh
Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
[ 1 ] - A comparison between the effects of Portulaca oleracea seeds extract and valsartan on echocardiographic and hemodynamic parameters in rats with levothyroxine-induced thyrotoxicosis
Objective: The aim of the present study was to compare the effects of Portulaca oleracea (Po) seeds extract and those of valsartan on cardiac function in levothyroxine (T4)-treated rats. Materials and Methods: Forty Wistar rats were divided into four groups (n=10): control, levothyroxine (T4), T4 plus valsartan (T4-Val) and T4 plus hydro-alcoholic extract of the P. oleracea seeds (T4-Po). Contr...
[ 2 ] - A comparison of the effects of Portulaca oleracea seeds hydro-alcoholic extract and Vitamin C on biochemical, hemodynamic and functional parameters in cardiac tissue of rats with subclinical hyperthyroidism
Objective: The present study was performed to evaluate the effects of hydro-alcoholic extract of Portulaca oleracea (P. oleracea) seeds and Vitamin C on biochemical and hemodynamic parameters in cardiac tissue of rats with subclinical hyperthyroidism. Materials and Methods: Forty eight male rats were divided into six groups of 8 and treated for 4 weeks. T4 group received daily injection of levo...
[ 3 ] - Kidney stone formation and antioxidant effects of Cynodon dactylon decoction in male Wistar rats
Objectives: The antioxidant capacity impairs in kidney and urinary bladder of animals with stone disease. Herbal medicine can improve the antioxidant condition of renal tissue. Cynodon dactylon (C. dactylon) is a medicinal plant with antioxidative and diuretic properties and different preparations of this plant have shown promising effects in stone disease. Assessment of the whole plant decocti...
[ 4 ] - Rheum turkestanicum rhizomes possess anti-hypertriglyceridemic, but not hypoglycemic or hepatoprotective effect in experimental diabetes
Objective: Rheum turkestanicum (R. turkestanicum) rhizomes have been used in Iranain traditional medicine as an anti-diabetic agent. The purpose of the present investigation was to evaluate the anti-diabetic and antioxidant activities of R. turkestanicum rhizome extract in streptozotocin-induced diabetic rats.Materials and Methods: Diabetes was induced by a single intraperitoneal injection of 5...
[ 5 ] - Renal injury, nephrolithiasis and Nigella sativa: A mini review
Objective: The incidence and prevalence of kidney stone is increasing worldwide. After the first recurrence the risk of subsequent relapses is higher and the time period between relapses is shortened. Urinary stones can be severely painful and make a huge economic burden. The stone disease may increase the vulnerability of patients to other diseases such as renal failure. Medicinal herbs are ri...
[ 6 ] - The protective effect of Nigella sativa against cisplatin-induced nephrotoxicity in rats
Objective: The clinical use of cisplatin is highly restricted, because of its nephrotoxicity.In this study the protective effect of Nigella sativa (N. sativa) against cisplatin-induced nephrotoxicity was investigated in rats. Materials and Methods: In the current study, the effects of the administration of aqueous-ethanolic extract of N. sativa (100 and 200 mg/kg, BW) and vitamin E (100 mg/kg, ...
[ 7 ] - Preventive effect of Cynodon dactylon against ethylene glycol-induced nephrolithiasis in male rats
Objective: This study was carried out to investigate the preventive effects of hydroalcoholic extract of Cynodon dactylon(C.dactylon) roots on calcium oxalate calculi in rat. Materials and Methods: 24 Wistar rats were randomly divided into 4 groups: group A received tap drinking water while, Groups B, C, and D received 1% ethylene glycol daily for 28 days. Rats in groups C and D received ethan...
[ 8 ] - Reduction of serum cholesterol in hypercholesterolemic rats by Guar gum
Objective: Several diseases are reported to be uncommon in those parts of the world where dietary fiber intakes are high, therefore, in this study; we evaluated the hypocholesterolemiceffects of a dietary fiber (guar gum) in hypercholesteromic rats. Materials and Methods: Rats were fed high-fat or a normal fed diet for 12-week then treated with 5% guar gum in their regime during a 28 days peri...
[ 9 ] - Effect of exogenous leptin on serum levels of lipids, glucose, renal and hepatic variables in both genders of obese and streptozotocin-induced diabetic rats
Objective(s): Leptin exerts various effects on appetite and body weight. Disruption of the obesitygene is precedent to fatness. Insulin or glucose elevates leptin, but streptozotocin reduces it. However, controversial data exist for the effects of leptin on diabetes and leptin level in each gender. Leptin can damage the kidney function but little evidence exists for its hepatic effects. The aim...
[ 10 ] - The prevention and treatment effects of egg yolk high density lipoprotein on the formation of atherosclerosis plaque in rabbits
Objective(s): Atherosclerosis is the main leading cause of cardiovascular diseases. The purpose of this study was to assess the potential preventive effect of egg yolk HDL on the atherosclerosis plaque formation. Materials and Methods: Thirty rabbits were divided into five groups: A; normal diet, B; hyper-cholesterolemic diet, C; hypercholesterolemic + 400 mg/kg egg yolk HDL D; hypercholesterol...
[ 11 ] - Hypothyroidism and Ramadan fasting
Introduction: Fasting during the holy month of Ramadan is an obligation for all adult, healthy Muslims. As several studies have indicated, both fasting and energy restriction can alter thyroid hormone metabolism and affect the clinical features and well-being of hypothyroid patients. Hypothyroidism is more prevalent among women and the elderly. Its prevalence has been reported to be 4-8% of the...
[ 12 ] - The anti-diabetic and antioxidant effects of a combination of Commiphora mukul, Commiphora myrrha and Terminalia chebula in diabetic rats
Objective: Effects of Commiphora mukul and Commiphora myrrha ethanolic extracts and Terminalia chebula<span style...
[ 13 ] - Ramadan Fasting and Thyroid Hormone Levels in Women with Hypothyroidism
Introduction: According to some studies, Ramadan fasting causes minimal changes in the levels of thyroid hormones. The present study aimed to evaluate the impact of Ramadan fasting on the levels of thyroid hormones in fasting women with hypothyroidism and levothyroxine intake. Methods: Serum levels of free thyroxine (T4) and thyroid-stimulating hormone (TSH) we...
[ 14 ] - The effects of lettuce extract on the level of T4, memory and nerve conduction velocity in male rats
Objective: According to the traditional medicine,lettuce can affect nerve conduction velocity and memory. So, to investigate the effect of lettuce seeds extract on body activities, lettuce seeds were used. Materials and Methods: In the present study, the effects of lettuce (Lactuca sativa) seeds extract consumption (in drinking water) on T4 level...
[ 15 ] - The role of Artemisia turanica extract on renal oxidative and biochemical markers in STZ-induced diabetes in rat
Objective: The aim of the current study was to investigate the protective effect of Artemisia turanica (AT) against diabetes- induced renal oxidative stress in rats. Materials and Methods: Fifty male Wistar rats were randomly divided into five groups: control, STZ-induced diabetic rats, diabetic rats+ metformin, diabetic rats + AT extract, diabet...
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