Lotfollah Rezagholizadeh
Department of Biochemistry, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
[ 1 ] - Renoprotective effects of the methanolic extract of Tanacetum parthenium against carbon tetrachloride-induced renal injury in rats
Objective: Studies have demonstrated that carbon tetrachloride (CCl4) increases the generation of reactive oxygen species (ROS) in many tissues including the kidney, heart, lung, brain, and liver. The major aim of the present study was to evaluate the protective activity of Tanacetum parthenium extract (TPE) in renal tissues of CCl4-intoxicated rats. Materials and Methods: Animals were divided ...
[ 2 ] - The protective effects of Tanacetum parthenium extract on CCl4-induced myocardium injury in rats
Background and Aim: The aim of this study was to investigate the protective effects of Tanacetum parthenium extract (TPE) on lipid peroxidation and acute heart injury induced by carbon tetrachloride (CCl4) in rats. Materials and Methods: In an experimental study, 30 male Wistar rats were divided into 5 groups (n=6). Two of the groups were normal and damage control groups, other 3 groups were d...
[ 3 ] - بررسی اثر هم افزایی عصاره هیدروالکلی دارچین و زنجبیل بر پارامترهای بیوشیمیایی خون در رت‌های آسیب دیده با تتراکلریدکربن
زمینه و هدف: با توجه به اهمیت سمیت کبدی ناشی از دارو و سموم بهعنوان یکی از عوامل آسیبرسان به بدن، این مطالعه با هدف ارزیابی اثرات ترکیب حاصل از عصارههای دارچین و زنجبیل بر پارامترهای بیوشیمیایی سرم در موشهای صحرایی آسیبدیده توسط تتراکلریدکربن (CCl4) انجام گرفت. روش کار: در این مطالعه تجربی، 42 سر موش صحرایی نر نژاد ویستار به 7 گروه 6 تایی تقسیم شدند. سه گروه کنترل شامل کنترل نرمال، کنترل ...
[ 4 ] - The role of hormones in renal disease and ischemia-reperfusion injury
The patients with renal diseases, especially end-stage renal disease (ESRD), are at high risk of developing cardiovascular disturbances. Some hormones such as brain natriuretic peptide appear to be important serum biomarkers in predicting cardiac death in ESRD patients. Renal diseases cause inflammation, anemia, uremic toxins, fluid overload, and electrolyte disturbance. Kidney transplantation ...
[ 5 ] - Hepatoprotective and Antioxidant Activities of Combination of Cinnamomum zeylanicum and Zingiber officinale in CCl4-intoxicated Rats
Introduction: Liver is the most important organ of drugs and xenobiotics metabolism and any damage to the liver is associated with dysfunction of this organ. This study was carried out to find the possible additive effect of the co-administration of Cinnamomum zeylanicum (cinnamon) and Zingiber officinale (ginger) extracts on carbon tetrachloride (CCl4</s...