Ikuko Mochida

Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine Osaka University Graduate School of Medicine Immunology Frontier Research Center

[ 1 ] - Whole-Body Distribution of Donepezil as an Acetylcholinesterase Inhibitor after Oral Administration in Normal Human Subjects: A 11C-donepezil PET Study

Objective(s): It is difficult to investigate the whole-body distribution of an orally administered drug by means of positron emission tomography (PET), owing to the short physical half-life of radionuclides, especially when 11C-labeled compounds are tested. Therefore, we aimed to examine the whole-body distribution of donepezil (DNP) as an acetylcholinesterase inhibitor by means of 11C-DNP PET ...

Co-Authors

Eku Shimosegawa 1  

Genki Horitsugi 1  

Hiroki Kato 1  

Jun Hatazawa 1  

Kayako Isohashi 1  

Keiko Matsunaga 1  

Sadahiro Naka 1  

Tadashi Watabe 1  

Yasukazu Kanai 1