H. Zolfagharian
[ 1 ] - Progress and improvement of the manufacturing process of snake antivenom
Antivenoms have been used successfully for more than a century and up to now constitute the only effective treatment for snakebites .The production of antivenin started long time ago when the calmette was prepared the antivenom in 1894.The method currently used to prepare antivenom by most of the manufacturers are originated from the method of Pope which was develop in 1938. Several new approac...
[ 2 ] - The Effects of Buthotus schach Scorpion Venom on Electrophysiological Properties of Magnocellular Neurons of Rat Supraoptic Nucleus
Potassium channels are trans-membrane proteins, which selectively transport K+ ions across cell membranes and play a key role in regulating the physiology of excitability cells and signal transduction pathways. Bothutous Schach (BS) scorpion venom consists of several polypeptides that could modulate ion channels. In this study, the effects of BS crude venom on passive and active electrophysiolo...
[ 3 ] - Partial Fractionation of Venoms from Two Iranian Vipers, Echis carinatus and Cerastes persicus Fieldi and Evaluation of Their Antiplatelet Activity
Platelet aggregation inhibitory effect and anticoagulant properties of fractions separated from the venoms of Cerastes persicus fieldi and Echis carinatus were investigated. The partial fractionation was performed on a Sephadex G-100 column. Two fractions separated from Cerastes persicus fieldi showed anti platelet aggregation activity on ADP (200 µM)-induced platelet aggregation (ca 80% inhibi...
[ 4 ] - The Effects of Buthotus schach Scorpion Venom on Electrophysiological Properties of Magnocellular Neurons of Rat Supraoptic Nucleus
Potassium channels are trans-membrane proteins, which selectively transport K+ ions across cell membranes and play a key role in regulating the physiology of excitability cells and signal transduction pathways. Bothutous Schach (BS) scorpion venom consists of several polypeptides that could modulate ion channels. In this study, the effects of BS crude venom on passive and active electrophysiolo...
[ 5 ] - Partial Fractionation of Venoms from Two Iranian Vipers, Echis carinatus and Cerastes persicus Fieldi and Evaluation of Their Antiplatelet Activity
Platelet aggregation inhibitory effect and anticoagulant properties of fractions separated from the venoms of Cerastes persicus fieldi and Echis carinatus were investigated. The partial fractionation was performed on a Sephadex G-100 column. Two fractions separated from Cerastes persicus fieldi showed anti platelet aggregation activity on ADP (200 µM)-induced platelet aggregation (ca 80% inhibi...
[ 6 ] - Voltage-Gated Sodium Channels Modulation by Bothutous Schach Scorpion Venom
Buthotus schach is one of the dangers scorpion in Iran that belong to the Buthidae family. Toxins are existing in venom scorpion, modulate the ion channels by blocking or opening the pore of the channel or by altering the voltage gating and useful as pharmacological tools. In the present study, we investigated the effect of venom and its obtained fractions by gel filtrations on electrophysiolog...
[ 7 ] - تأثیر تمرینات هوازی بر شاخص های هماتولوژی در اسب‌های تولید کننده پادزهر
ایران جزء تولیدکنندگان منحصر به فرد پادزهر در منطقه خاورمیانه است. تولید سرم‌های درمانی با عیار بالا و عوارض جانبی کمتر در سلامت عمومی جامعه تأثیر بسزایی دارد. این امر تنها زمانی میسر خواهد بود که بهداشت دام، تأمین شود. بکارگیری فعالیت‌های ورزشی به عنوان روش غیر دارویی می‌تواند در حفظ و ارتقا سلامت دام نقش مهمی ایفا کند. هدف از پژوهش حاضر مطالعه تأثیر تمرینات هوازی بر فاکتورهای هماتولوژی در اسب...
[ 8 ] - Evaluation of Anticancer Effects Induced by Apis mellifera Venom on Breast Cancer Cell Line
Background: In recent years, the number of people with cancer has increased. For this reason, different drugs have been suggested for the treatment of cancer, but none of them has resulted in complete remission. Many bio-toxins are biologically active compounds with anticancer activity. In the meantime, bee venom (BV) has a potent anti cancer and tumor effects. The aim of present study is evalu...
[ 9 ] - Biochemical and oxidative response of antibody-producing horses to moderate aerobic activity
Back ground: The bites of animals such as snakes and scorpions are among the most important problems related to human health, so that scorpion bites are the cause of the highest deaths due to the bites of poisonous organisms in the world.Scorpion bites are one of the major and important problems that cause losses in different regions according to lifestyle, socio-economic status, housing status...
Co-Authors