فراز مجاب
استاد گروه فارماکوگنوزی، مرکز تحقیقات علوم دارویی، دانشکده داروسازی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.
[ 1 ] - بررسی تأثیر کپسول عصاره هیدروالکلی گیاه بومادران بر طول مدت زمان و شدت دیسمنوره اولیه
مقدمه: دیسمنوره یکی از شایع‌ترین مشکلات ژنیکولوژیک زنان است. داروهای شیمیایی، گیاهی، طب سوزنی و فشاری و ماساژ درمانی انواع روش‌های درمانی دیسمنوره است. با توجه به تأثیر احتمالی بومادران بر دیسمنوره و فقدان مطالعات کافی در این زمینه، مطالعه حاضر با هدف بررسی تأثیر کپسول عصاره هیدروالکلی گیاه بومادران بر طول مدت زمان و شدت دیسمنوره اولیه زنان انجام شد. روشکار: این مطالعه کارآزمایی بالینی کنترل ش...
[ 2 ] - تأثیر لوسیون میوه عناب بر بهبود درد شقاق پستان زنان نخست‌زا شیرده
مقدمه: درد همراه با شقاق پستان یکی از مشکلات شایع دوران شیردهی است که می‌تواند باعث قطع زودهنگام شیردهی شود. میوه عناب یکی از قدیمی‌ترین گونه‌های دارویی است که ترکیبات ضد دردی و ضد التهابی دارد، مطالعه حاضر با هدف تعیین تأثیر لوسیون میوه عناب بر بهبود درد نوک پستان انجام شد. روشکار: این مطالعه کارآزمایی بالینی دوسوکور در سال 1394 بر روی 100 نفر از زنان نخست‌زا شیرده دارای درد نوک پستان در درم...
[ 3 ] - مقایسه رایحه اسانس میخک و نعناع فلفلی بر شدت درد و اضطراب مرحله اول زایمان
مقدمه: امروزه استفاده از روش‌های غیر دارویی و طب مکمل به منظور کاهش درد و اضطراب زایمان رو به افزایش است، لذا مطالعه حاضر با هدف مقایسه رایحه اسانس میخک و نعناع فلفلی بر شدت درد و اضطراب مرحله اول زایمان انجام شد. روشکار: این کارآزمایی بالینی در سال 1393 بر روی 126 نفر از زنان نخست‌زای مراجعه کننده به بیمارستان کمالی کرج به تفکیک در دو گروه میخک (63 نفر) و نعناع فلفلی (63 نفر) انجام گردید. رای...
[ 4 ] - تأثیر کرم گل ماهور بر شدت درد اپی زیاتومی در زنان نخست زا
مقدمه: اپی زیاتومی شایع ترین جراحی در مامایی است که جهت تسهیل خروج جنین انجام می شود. درد ناشی از اپی زیاتومی کیفیت زندگی مادر را تحت تأثیر قرار می دهد. گل ماهور از زمان های قدیم برای درمان بیماری های مختلف استفاده می‌شده است. از آنجایی که تاکنون مطالعه‌ای جهت بررسی اثرات تسکین درد گل ماهور در مدل‌های انسانی انجام نشده است، لذا مطالعه حاضر با هدف بررسی تأثیر کرم گل ماهور بر شدت درد اپی زیاتومی ...
[ 5 ] - تأثیر کرم گل راعی بر کاهش درد پرینه بعد از اپی زیاتومی در زنان نخست زا
مقدمه: اپی زیاتومی یک برش جراحی در مدخل واژن است که با برش پرینه در مرحله دوم لیبر انجام می‌گیرد. گل راعی به دلیل دارا بودن تانن و هیپرسین و هیپرفورین دارای خاصیت ضد درد می‌باشد. مطالعه حاضر با هدف بررسی تأثیر کرم گل راعی بر کاهش درد پرینه بعد از اپی زیاتومی انجام شد. روش کار: این مطالعه کارآزمایی بالینی تصادفی دوسوکور در سال 1393 بر روی 100 زن واجد شرایط پژوهش مراجعه‌کننده به بیمارستان نورانی ...
[ 6 ] - The effect of Saqez (Pistacia atlantica) ointment on nipple fissure improvement in breastfeeding women during one-month follow-up
Objective: Painful nipple fissure is a troublesome problem for breastfeeding mothers. This study was conducted to evaluate the effect of saqez (Pistacia atlantica) ointment on the improvement of nipple fissure in breastfeeding women during one-month follow-up. Materials and Methods: This randomized controlled clinical trial was conducted on 100 eligible women who visited the selected health cen...
[ 7 ] - Antimalarial natural products: a review
Objective: Malaria is an infectious disease commonplace in tropical countries. For many years, major antimalarial drugs consisted of natural products, but since 1930s these drugs have been largely replaced with a series of synthetic drugs. This article tries to briefly indicate that some plants which previously were used to treat malaria, as a result of deficiencies of synthetic drugs, have rev...
[ 8 ] - Effect of inhalation of Lavender essential oil on vital signs in ICU open-heart surgery
This study evaluated the effects of inhalation of Lavender essential oil on vital signs in ICU open-heart surgery. This study is a clinical single-blind trial. The study was conducted on 40 patients who had open-heart surgery in the Cardiac ICU of two Hospitals of Tehran University of Medical Sciences, 2012. Criteria included: full Consciousness, lack of hemorrhage, lack of heart rate reduction...
[ 9 ] - Urease Inhibitory Activities of some Commonly Consumed Herbal Medicines
Urease enzyme has a crucial role in the persistent habitation of Helicobacter pylori (H. pylori) that induces gastrointestinal diseases, in particular gastritis, duodenal, peptic ulcer, and gastric cancer. Plants have long been utilized as the biggest source of substances with medicinal properties from natural origin and therefore result in less toxicity and adverse side effects upon usage. 15 ...
[ 10 ] - Effect of inhalation of Lavender essential oil on vital signs in ICU open-heart surgery
This study evaluated the effects of inhalation of Lavender essential oil on vital signs in ICU open-heart surgery. This study is a clinical single-blind trial. The study was conducted on 40 patients who had open-heart surgery in the Cardiac ICU of two Hospitals of Tehran University of Medical Sciences, 2012. Criteria included: full Consciousness, lack of hemorrhage, lack of heart rate reduction...
[ 11 ] - Urease Inhibitory Activities of some Commonly Consumed Herbal Medicines
Urease enzyme has a crucial role in the persistent habitation of Helicobacter pylori (H. pylori) that induces gastrointestinal diseases, in particular gastritis, duodenal, peptic ulcer, and gastric cancer. Plants have long been utilized as the biggest source of substances with medicinal properties from natural origin and therefore result in less toxicity and adverse side effects upon usage. 15 ...
[ 12 ] - Effect of powder sizes, pH of water, ultrasound and method of distillation on extraction of fennel essential oil
The essential oils are frequently used in food processing industry, perfumery, cosmetics and pharmaceuticals. Most of the oils obtained by steam distillation and water distillation. It is necessary to specify the best conditions of essential oils production to get much more major compound(s) and higher yield oil. So, fennel oil was selected in this study. The objective of this work was to ident...
[ 13 ] - The Essential oil Composition of Arctium lappa Root and Leaf
Using plants and natural products as medicine is increasing every day. The reason might be a tendency that the societies mostly have toward natural and original products especially natural drugs. Essential oilsare referred to aromatic composition which is found in different parts of a plant and can be used for different remedial and hygienic purposes. One of the plants which have been used a lo...
[ 14 ] - An In-Vivo Study on Anticonvulsant, Anxiolytic, and Sedative-Hypnotic Effects of the Polyphenol-Rich Thymus Kotschyanus Extract; Evidence for the Involvement of GABA-A Receptors
Antidepressant-like activity of T. kotschyanus has been recently reported by scientists but insufficient attention has so far been devoted to T. kotschyanus, and there is a lack of information on the other neurobehavioral effects and side effects of this species. In the current study, the anticonvulsant, anxiolytic and sedative-hypnotic, effects of Thymus kotschyanus extract on male NMRI mic...
[ 15 ] - Effects of Some Lamiaceae Species on NO Production and Cell Injury in Hydrogen Peroxide-induced Stress
Nitric oxide (NO) is a key mediator that plays an important role in pathogenesis of various chronic diseases like Alzheimer’s disease and Parkinson’s disease. Additionally, there is a great attitude for finding natural compounds, which could control and inhibit NO production in pathological conditions. Therefore, we were encouraged to investigate the effects of some Lamiaceae species on NO prod...
[ 16 ] - An In-Vivo Study on Anticonvulsant, Anxiolytic, and Sedative-Hypnotic Effects of the Polyphenol-Rich Thymus Kotschyanus Extract; Evidence for the Involvement of GABA-A Receptors
Antidepressant-like activity of T. kotschyanus has been recently reported by scientists but insufficient attention has so far been devoted to T. kotschyanus, and there is a lack of information on the other neurobehavioral effects and side effects of this species. In the current study, the anticonvulsant, anxiolytic and sedative-hypnotic, effects of Thymus kotschyanus extract on male NMRI mic...
[ 17 ] - Effects of Some Lamiaceae Species on NO Production and Cell Injury in Hydrogen Peroxide-induced Stress
Nitric oxide (NO) is a key mediator that plays an important role in pathogenesis of various chronic diseases like Alzheimer’s disease and Parkinson’s disease. Additionally, there is a great attitude for finding natural compounds, which could control and inhibit NO production in pathological conditions. Therefore, we were encouraged to investigate the effects of some Lamiaceae species on NO prod...
[ 18 ] - Chemical Compounds Isolated from Aerial Part of Primula auriculata L.
Arial parts of Primula genus (Primulaceae) are well known to treat various ailments in Iranian Traditional Medicine. Our preliminary studies showed that the medium polar to polar extracts of Primula auriculata had a significant cytotoxic activity and Induction of apoptosis effects on some cancerous cell lines. The current study focused on phytochemical investigation and characterization the com...
[ 19 ] - A Double-Blind, Randomized, Placebo-Controlled Trial, Evaluating the Efficacy of Commiphora Mukul Cream in Improving Breast Engorgement in Breastfeeding Women
Breast engorgement is a common problem during breastfeeding that can lead to early discontinuation of breastfeeding. Commiphora Mukul (C. Mukul) is a medicinal plant with analgesic and anti-inflammatory compounds. The present study was conducted to determine the effect of C. Mukul on improving breast engorgement in breastfeeding women. This study was a double-blind, randomized, and placebo-cont...
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