سعید عباسی ملکی
[ 1 ] - تأثیر عصاره هیدروالکلی جو دوسر بر علایم سندرم محرومیت مورفین در موش سوری نر
زمینه و هدف: مطالعات نشان دادند که برخی از داروهای ضد افسردگی سبب کاهش علایم سندرم محرومیت اوپیوئیدها می‌شوند. از طرفی مطالعات انجام شده حاکی از خواص ضد افسردگی و آرام‌بخشی جو دوسر می‌باشند. هدف مطالعه حاضر بررسی تأثیر عصاره هیدروالکلی جو دوسر بر علایم سندرم محرومیت مورفین در موش سوری نر بوده است. مواد و روش‌ها: در این مطالعه تجربی، 40 سر موش سوری نر نژاد NMRI (20 الی 30 گرم) به‌طور تصادفی به ...
[ 2 ] - Evaluation of antidepressant-like effects of aqueous and ethanolic extracts of Pimpinella anisum fruit in mice
Objective: Pimpinella anisum (P. anisum) has different pharmacological properties such as anticonvulsant, analgesic, tranquilizer, antidepressant and anti-anxiety effects. In this study the antidepressant-like effect of aqueous and ethanolic extracts of P. anisum fruit in mice was investigated. Materials and Methods: Forced swimming test (FST) and tail suspension test (TST) were used to determ...
[ 3 ] - Suppressive Effects of Rosa Damascena Essential Oil on Naloxone-Precipitated Morphine Withdrawal Signs in Male Mice
This research was done to test the effect of Rosa damascena essential oil on withdrawal signsof naloxone-precipitated morphine in male mice. Morphine dependence was induced by injection(IP) three times daily at doses of 50, 50 and 75 mg/kg, respectively, for 3 days. On day 4,after the last administration of morphine, Rosa damascena essential oil was administered atdifferent concentrations (5, 2...
[ 4 ] - Suppressive Effects of Rosa Damascena Essential Oil on Naloxone-Precipitated Morphine Withdrawal Signs in Male Mice
This research was done to test the effect of Rosa damascena essential oil on withdrawal signsof naloxone-precipitated morphine in male mice. Morphine dependence was induced by injection(IP) three times daily at doses of 50, 50 and 75 mg/kg, respectively, for 3 days. On day 4,after the last administration of morphine, Rosa damascena essential oil was administered atdifferent concentrations (5, 2...
[ 5 ] - بررسی اثر سیتالوپرام بر علایم سندرم محرومیت مورفین در موش سوری نر
Background and Objectives: Serotonergic system has a role in procedure of morphine dependence and withdrawal signs incidence. On the other hand it has been shown that antidepressants may reduce the abuse susceptibility of opioids . So, the aim of this study was to investigate the effect of citalopram as a selective serotonin reuptake inhibitor (SSRIs) antidepressant on morphine withdrawal sig...
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