پوران لایق

[ 1 ] - اثربخشی مدیریت استرس به شیوه شناختی -رفتاری بر اضطراب، افسردگی و کیفیت زندگی بیماران مبتلا به پسوریازیس

مقدمه شیوع بالای اختلالات روانی در بیماران مبتلا به بیماری های پوستی در تحقیقات متعددی تایید شده است. پسوریازیس یک بیماری مزمن پوستی است که جنبه روان - تنی داشته و تحقیقات مختلف بیانگر ظهور یا تشدید علائم بیماری با عوامل روانشناختی می باشد. همچنین مطالعات نشان دهنده شیوع بالاتر اضطراب و افسردگی در بیماران پسوریازیس نسبت به جمعیت عمومی است. پسوریازیس بر کیفیت زندگی این بیماران نیز تأثیر زیادی دا...

[ 2 ] - Survey on Etiology of Stevens-Johnson syndrome and Toxic Epidermal Necrolysis in Pediatric Patients: A Six-Year Study from Iran

Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are among the most severe dermatologic reactions to the drugs. Data about SJS and TEN among pediatric population especially in Iran is limited. This study aimed to investigate the clinical and para-clinical characteristics of pediatric patients with SJS/TEN. Materials and Methods From 2010 to 2016, all SJS and TEN c...

[ 3 ] - H Syndrome Masquerade as Rheumatologic Disease

Background  H syndrome is an autosomal recessive genodermatosis with a low prevalence which is caused by a mutation in SLC29A3 gene. This disorder is characterized by sclerotic, hyperpigmented, hypertrichotic cutaneous plaques with systemic involvement including: hepatosplenomegaly, heart anomalies, hearing loss, hypogonadism, low height, and hyperglycemia. Case Presentation  Here we have pres...

[ 4 ] - Antileishmanial Activity of Liposomal Clarithromycin against Leishmania Major Promastigotes

Objective(s)Cutaneous leishmaniasis is a common parasitic disease which is endemic in some parts of the world. In vitro and in vivo studies have shown azithromycin efficacy on some Leishmania species. Because of structural similarity between clarithromycin and azithromycin and efficacy of clarithromycin against intracellular organisms and due to the absence of previous studies in this respect, ...

[ 5 ] - Propranolol for infantile hemangioma: An evaluation of its efficacy and safety in Iranian infants

Background: Propranolol has been recently indicated to inhibit the rapid growth and involution of infantile hemangioma. In the present study, we investigated the efficacy and safety of propranolol in Iranian infants. Methods: A total of 30 infants with indications for medical intervention, such as large hemangiomas, wounds with or without secondary infection, or active trauma-induced bleeding,...

[ 6 ] - The efficacy of Isotretinoin-loaded solid lipid nanoparticles in comparison to Isotrex® on acne treatment

Topical retinoids are considered as the first line therapy in the treatment of acne vulgaris, but they are associated with cutaneous irritation. In this study, isotretinoin-loaded solid lipid nanoparticles(IT-SLN) were prepared to treat the mild to moderate acne. Also using IT-SLN would minimize IT adverse effects in comparison to commercial product, Isotrex®. This study was conducted to prepar...

[ 7 ] - مقایسه‌ی تستوسترون آزاد بزاق با تستوسترون آزاد سرم در بیماران مبتلا به هیرسوتیسم و گروه شاهد

Background and Aim: Hirsutism is defined as male pattern hair growth in females which affects 10% of women. Our aim was to compare free salivary and free serum testosterone levels in women with hirsutism and healthy controls.Methods: This study was a case-control study in which 30 hirsute women in child bearing age were recruited and compared with 10 healthy controls. For each patient, a questi...

[ 8 ] - Evaluation of Quality of Life, Anxiety and Depression in Children with Cutaneous Leishmaniasis

Background Cutaneous leishmaniasis (CL) is a common parasitic infectious disease which is distributed worldwide. Despite low morbidity rate, the disorder negatively impacts on psychological well-being and social life of patients. We aimed to evaluate the frequency of psychiatric morbidity including depression and anxiety levels as well as quality of life (QOL) in...

[ 9 ] - A pink papule on the forehead of a young woman

[ 10 ] - The Role of Staphylococcus Aureus Types and Toxin-Producing Ability in Pediatric Atopic Dermatitis and its Association with Disease Severity

Background: The skin of patients with atopic dermatitis has a high susceptibility to staphylococcus aureus (S. aureus) colonization known to produce toxins with super antigen (SAgs) activity which are a family of potent immune-stimulatory exotoxins and may aggravate AD. The aim of this research was to evaluate the ro...