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استاد / گروه داخلی بیمارستان قائم دانشگاه علوم پزشکی مشهد

[ 1 ] - جدا سازی نوموسیستیس جیرووسی ازبیماران ریوی با یا بدون نقص ایمنی ( یک مطالعه مولکولی )

مقدمه :ذات الریه نوموسیستییکی ازجدی ترین عفونت های تهدید کننده زندگی در بیماران دارای ویروس نقص ایمنی اکتسابی می باشد.هم چنین می تواند در بیماران دچار سرکوب ایمنی که تحت درمان با داروهای کاهش دهنده ایمنی هستند رخ دهد.  افراد با ایمنی سالم نیز می توانند ناقل نوموسیستیس جیرووسی باشند. هدف از این مطالعه بررسی وجود و  فراوانی نوموسیستیس جیرووسی در بیماران ریوی بود. روش کار:در این مطالعه توصیفی مقطع...

[ 2 ] - شاخص توده بدنی و آلبومین سرم در بیماران مبتلا به بیماری مزمن انسدادی ریه «مرکز تحقیقات بیماریهای ریوی و سل »

مقدمه بیماری مزمن انسدادی ریوی با التهاب مزمن و محدودیت پیشرونده جریان هوای بازدمی مشخص می شود. اخیرا علاوه بر علائم ریوی تظاهرات مختلف خارج ریوی مثل کاهش وزن و اختلالات تغذیه ای شرح داده شده که تحت عنوان علائم سیستمیک یا عمومی این بیماری نام برده می شود. در این مطالعه شاخص توده بدنی و آلبومین سرم این بیماران اندازه گیری و ارتباط آن با تستهای عملکرد ریوی مورد بررسی قرار گرفته است. روش کار این م...

[ 3 ] - Level of Eosinophil Cationic Protein in Sputum of Chemical Warfare Victims

Objective(s) Considering fair response to inhaled corticosteroids and reports of severe air way hyper responsiveness in chemical warfare victims (CWV), a role for eosinophilic inflammation (i.e. asthma) was postulated. The objective of this study was to determine the presence of eosinophilic inflammation in CWV by evaluation of Sputum cellularity and eosinophil cationic protein (ECP). Materials...

[ 4 ] - The evaluation of e-health adoption by Iranian citizens

The advances in the diagnosis and management of diseases, especially chronic conditions, necessitates the development of health care systems and are time-consuming. The introduction of e-health system as an efficient tool for the management and care of patients in the recent decades has resulted in a significant success in this regard. However, the implementation of this system accompanies with...

[ 5 ] - Early Effectiveness of Noninvasive Positive Pressure Ventilation on Right Ventricular Function in Chronic Obstructive Pulmonary Disease Subjects with Acute Hypercapnic Respiratory Failure

Introduction: Noninvasive positive pressure ventilation (NIPPV) has become an integral tool in the management of acute hypercapnic respiratory failure (AHRF) in chronic obstructive pulmonary disease (COPD). This study was performed to evaluate the early effects of NIPPV on pulmonary artery pressure (PAP), serum N-terminal pro BNP (NT-proBNP), and ventilatory parameters in the COPD patients with...

[ 6 ] - Determination of The Relationship Between Severity of Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease

Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate the severity of OSAHS in overlap syndrome patients.Materials & Methods: This cross-sectional study was conducted on adult patients with forced...

[ 7 ] - Video-assisted Thoracoscopic Surgery Versus Axillary Thoracotomy in Primary Spontaneous Pneumothorax

Introduction: Video-assisted thoracic surgery (VATS) is now commonly used for primary spontaneous pneumothorax. In the present study we compared the outcomes of this technique with those obtained by conventional thoracotomy.Material and Methods: In this cross-sectional stud, forty patients were enrolled into two groups: VATS (n=20) and thoracotomy (n=20). In both groups the blebs were resected ...

[ 8 ] - The Role of EDD (Exercise Capacity, Dyspnea, and Diffusing Capacity of Lungs for Carbon Monoxide) Index in Pulmonary Fibrosis Secondary to Scleroderma

Introduction: Pulmonary involvement secondary to Systemic Sclerosis (SSc) is the major cause of morbidity and mortality in SSc patients. We designed this study to determine the correlation of important lung function parameters with lung High Resolution CT (HRCT) scan findings. Materials and Methods: Thirty–two consecutive diffuse SSc patients with pulmonary fibrosis were enrolled in this cross...

[ 9 ] - Evaluation of Superiority of FEV1/VC Over FEV1/FVC for Classification of Pulmonary Disorders

Introduction: Forced expiratory value in one score  (FEV1)/ Forced vital capacity (FVC) was used in classical literature for primary classifications of pulmonary disorders. American Thoracic Society/ European Respiratory Society guidelines recommended using FEV1/VC instead of FEV1/FVC.The aim of study was determination of the extent of superiority of FEV1/VC over the FEV1/FVC. Materials and Met...

[ 10 ] - The Evaluation of Diastolic Hypertention in Sleep Overlap Syndrome

Introduction:The overlap syndrome, consisting ofobstructive sleep apnea hypopnea syndrome (OSAHS) and chronic obstructvie pulmonary disease (COPD) is a major problem in COPD patients. OSHAS corresponds to the likelihood of systemic hypertension.The present study was aimed to evaluate the association between apnea-hypopnea index and diastolic blood presssure (DBP) in overlap  patients. Materials...

[ 11 ] - Metabolic Syndrome in Chemical Warfare Patients with Chronic Obstructive Pulmonary Disease

  Introduction: Sulfur mustard (SM), a toxic alkylating gas, can cause serious long-term pulmonary complications such as chronic obstructive pulmonary disease (COPD). Metabolic syndrome (MetS) is one of the important comorbidities of COPD. This study was designed to evaluate the frequency of metabolic syndrome in Iranian chemical warfare patients (CWPs) with COPD. Materials and Methods: Thirty ...

[ 12 ] - The Relationship between Serum Pro‐Brain Natriuretic Peptide (Pro‐BNP) Levels and Pulmonary Arterial Hypertension (PAH) in Patients with Limited Scleroderma

Introduction: Pulmonary arterial hypertension (PAH) is a late progressive sclerodermarelated complication, which can lead to right heart failure and cor pulmonale. Given that cardiac catheterization is a diagnostic method of choice for PAH, and considering the high risks of this method, the purpose of this study was to evaluate the relationship between serum Pro‐Brain natriuretic peptide (Pro‐B...

[ 13 ] - The Relationship between Diaphragmatic Movements in Sonographic Assessment and Disease Severity in Patients with Stable Chronic Obstructive Pulmonary Disease (COPD)

Introduction: Pulmonary hyperinflation in patients with chronic obstructive pulmonary disease (COPD) can increase the breathing rate and reduce diaphragmatic movements by pushing the diaphragms downward and limiting their movements; this, in fact, can affect the breathing process. The purpose of this study was to compare diaphragmatic movements in COPD patients and healthy ones and to evaluate ...

[ 14 ] - A comparison of HTLV-1 Infection Frequency in Patients with or without Tuberculosis

Introduction: To recognize the predisposing factors in tuberculosis as an endemic infection in Northeast province of Iran, this study was aimed to evaluate whether HumanT-lymphocyte type 1 (HTLV-I) as an immunosuppressive factor increases the risk of tuberculosis. Materials and Methods: A Case-control study was conducted in 278 tuberculosis patients from 2007 to 2010, in Mashhad, Iran. Tubercul...

[ 15 ] - The Assessment of Health-Related Quality of Life in Scleroderma-Interstitial Lung Disease

Introduction: Pulmonary involvement is the most common cause of mortality and disability in patients with systemic sclerosis and it significantly affects the quality of life in these patients. Therefore, early diagnosis and treatment of pulmonary involvement seems necessary in patients with SSc. In this study, we aimed to assess the health-related quality of life (HRQoL) in patients with Sclero...

[ 16 ] - Lipid Profile Status in Mustard Lung Patients and its Relation to Severity of Airflow Obstruction

Introduction: Chronic obstructive pulmonary disease (COPD) secondary to sulfur mustard gas poisoning, known as mustard lung, is a major late pulmonary complications in chemical warfare patients. Serious comorbidities like dyslipidemia are frequently encountered in COPD. The aim of this study was to measure the serum lipid profile and evaluate the relation of lipid parameters with the severity o...

[ 17 ] - Bilateral Pulmonary Artery, Inferior Vena Cava, and Cardiac Echinococcosis: A Rare Presentation of Zoonotic Diseases

Introduction:Cystic hydatidosis is a zoonoticdisease thatis mostly observedin the Mediterranean region. This infectious disease may present throughdifferent manifestations that may delay the diagnosis and cause various complications for the patients. Most of the cases are usually diagnosed by imaging studies and the related management could be medical or surgical depending on the patient’s clin...

[ 18 ] - Sentinel Node Mapping in Non-small Cell Lung Cancer Using an Intraoperative Radiotracer Technique

 Objective(s): Lymph node metastases are the most significant prognostic factor in localized non-small cell lung cancer (NSCLC). Identification of the first nodal drainage site (sentinel node) may improve detection of metastatic nodes. Extended surgeries, such as lobectomy or pneumonectomy with lymph node dissection, are among the therapeutic options of higher acceptab...

[ 19 ] - Evaluation of Pulmonary Function Test in Patients with Amyotrophic lateral sclerosis and its correlation with the symptoms of the disease

Introduction: Amyotrophic lateral sclerosis (ALS) is a neurogenic progressive disease that leads to muscle atrophy. The purpose of this study was to evaluate pulmonary function test (PFT) in patients with ALS and its correlation with ASL symptoms. Materials and Methods: This cross-sectional study was performed on 32 ALS patients at Ghaem Hospital, Mashhad...

[ 20 ] - The accuracy of FEF25-75/ FVC for primary classification of the pulmonary function test

Introduction: The forced expiratory flow at 25 and 75% of the pulmonary volume/forced vital capacity ratio (FEF25-75/FVC) as a spirometry parameter has been successful in the early diagnosis of chronic obstructive pulmonary disease (COPD) and the methacholine challenge test for assessing airway responsiveness.To determine the accuracy of FEF25-7...