Seyed Erfan Mortazavi
Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
[ 1 ] - Minocycline improves memory in a passive avoidance task following cerebral ischemia-reperfusion by enhancing hippocampal synaptic plasticity and restoring antioxidant enzyme activity in rats
Introduction: Oxidative stress plays a crucial role in the impairment of synaptic plasticity following cerebral ischemia which ultimately results in memory dysfunction. Hence, application of antioxidant agents could be beneficial in the management of memory deficit after brain ischemia. Minocycline is a tetracycline antibiotic with antioxidant effect. The main objective of this work was to asse...
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