Zangooei, Mohammad

Department of Biochemistry, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran

[ 1 ] - Effect of Hesperetin on the level of reactive oxygen species (ROS) in gastric cancer stem cells: Short Communication

Intracellular reactive oxygen species (ROS) play an important role in cancer stem cell (CSC) function. Hesperetin (Hst) is a flavonoid that has been shown to affect cellular ROS level. The goal of this study was to investigate the effect of Hst on the level of ROS in gastric CSCs (GCSCs). MTT assay was used to evaluate cell survival. Cellular ROS level was measured using 2′,7′-dichlorofluoresci...

[ 2 ] - Effect of hesperetin on interleukin-8 gene expression in MCF-7 cell line: Short Communication

Breast cancer is recognized as the most common cause of cancer deaths in women. So far, no definite treatment has been identified there is no certain cure for breast cancer. The Ooverexpression of interleukin-8 is associated with increased tumor growth and breast cancer metastasis. Hesperetin is a flavonone sub-group of flavonoids that is abundantly found in citrus fruits, including lemons and ...