Farahnaz Jazaeri
Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. |Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
[ 1 ] - Current Models for Predicting Drug-induced Cholestasis: The Role of Hepatobiliary Transport System
Drug-induced cholestasis is the main type of liver disorder accompanied by high morbidity and mortality. Evidence for the role of hepatobiliary pumps in the cholestasis patho-mechanism is constantly increasing. Recognition of the interactions of chemical agents with these transporters at the initial phases of drug discovery can help develop new drug candidates with low cholestasis potential. Th...
[ 2 ] - Current Models for Predicting Drug-induced Cholestasis: The Role of Hepatobiliary Transport System
Drug-induced cholestasis is the main type of liver disorder accompanied by high morbidity and mortality. Evidence for the role of hepatobiliary pumps in the cholestasis patho-mechanism is constantly increasing. Recognition of the interactions of chemical agents with these transporters at the initial phases of drug discovery can help develop new drug candidates with low cholestasis potential. Th...
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