Bahman Soufiani, Katayoun

PhD Candidate, Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

[ 1 ] - Gene manipulation of human adipose-derived mesenchymal stem cells by miR-34a

Background: Safe and effective gene therapy is considered as one of the therapeutic goals in many diseases. Due to the important role of stem cells in cell therapy, this study aimed to produce human adipose-derived mesenchymal stem cells (hASCs) using the miR-34a overexpression. Materials and methods: The hsa-mir-34a precursor sequence was cloned into the PCDH lentiviral vector. The recombinant...