Majid Moradmand

Department of Animal and Plant Biology, Faculty of Biological Sciences and Technology, University of Isfahan. Isfahan, Iran.

[ 1 ] - The Effect of Omega-lycotoxin on the Cognitive Impairment induced by Kainic acid in Rats

Background: Excitotoxicity is a common pathological process in neurodegenerative diseases associated with overactivity of N-methyl-D-aspartate (NMDA) and P/Q type voltage-gated calcium (Cav2.1) channels. Omega-lycotoxin-Gsp2671g is a therapeutic tool to modulate overactive Cav2.1 (P/Q type) channels. Omega-lycotoxin binds to Cav2.1 channels with high affinity and selectivity. This study aimed t...