Mahmoudi, Seyedeh Shima
Qazvin university of Medical Sciences
[ 1 ] - The effects of chronic administration of pioglitazone on learning and memory in streptoztocin rat model of Alzheimer’s disease
Background: Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by abnormal protein accumulation, synaptic dysfunction, and cognitive impairment. Peroxisome proliferator-activated gamma receptors (PPARγ) play a crucial role in regulating insulin sensitivity and may serve as potential therapeutic targets for AD. Pioglitazone (Piog) as a PPARγ agonist reduce β-amyloid ...
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