Mohammad Ganji, Shahla
Molecular Medicine Department, National Institute of Genetic Engineering and Biotechnology
[ 1 ] - MLH1 Gene Expression and Pathologic Factors in Iranian Patients with Colorectal Cancer
Background and Objectives: MutL homolog (MLH1) is a key component of heterodimeric complex MutLα, which recognizes and repairs base-base mismatches or insertion/deletion loops that arise from nucleotide misincorporation. In the absence of MLH1 protein, the number of unrepaired mismatches will increase and cause tumors in organs. The present study aimed at quantitative analysis of MLH1 gene expr...
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