Stacy Rampersad
Laboratory of Peptide Research and Development, School of Pharmacy, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
[ 1 ] - Synthesis and Bioactivity of a Cyclopolypeptide from Caribbean Marine Sponge
Synthesis of a natural proline-rich cyclopolypeptide - rolloamide A [8] was carried out by coupling of tri- and tetrapeptide units Boc-Phe-Pro-Val-OMe and Boc-Pro-Leu-Pro-Ile-OMe after proper deprotection at carboxyl and amino terminals using carbodiimide chemistry in alkaline environment followed by cyclization of linear heptapeptide segment in the presence of base. The structure of synthesize...
[ 2 ] - Synthesis and Bioactivity of a Cyclopolypeptide from Caribbean Marine Sponge
Synthesis of a natural proline-rich cyclopolypeptide - rolloamide A [8] was carried out by coupling of tri- and tetrapeptide units Boc-Phe-Pro-Val-OMe and Boc-Pro-Leu-Pro-Ile-OMe after proper deprotection at carboxyl and amino terminals using carbodiimide chemistry in alkaline environment followed by cyclization of linear heptapeptide segment in the presence of base. The structure of synthesize...
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