Roshanbakhsh, Hannaneh
MSc in Physiology, Faculty of Biology, Damghan University, Damghan, Iran
[ 1 ] - Effects of Piperine Pretreatment on Antioxidant Capacity and Spatial Memory Impairment Induced by Local Injection of Lysolecethin in Rat Hippocampus
Background and purpose: Piperine as the main alkaloid of black pepper has antioxidant and neuroprotective properties, so, it is an appropriate candidate to be studied in animal models of multiple sclerosis. This research aimed at investigating the effect of pretreatment with piperine on spatial memory, oxidative stress, and myelin repair gene markers in local demyelination model. Materials and...
[ 2 ] - Piperine pre-treatment has immunomodulatory effects in hippocampal local model of demyelination
Introduction: Inflammatory processes has an important role in the Multiple Sclerosis (MS)’s pathophysiology. Therefore, hampering the inflammatory factors could be an effective strategy in MS treatment. Piperine (the main alkaloid of black piper) has immunomodulatory and anti-inflammatory properties. In this study the pre-treatment effects of piperine on the gene expression level of inflammator...