Zarei L

[ 1 ] - P-161: Deleterious Side Effects of Methotrexate on In Vitro Fertilization and Protective Role of Cornus Mas Extract in Adult Mice

Background: Because of stress oxidative side effect of MTX on reproductive system, current study was aimed to evaluate protective effects of cornus mas fruit extract (CMFE) in mice treated with methotrexate (MTX). Materials and Methods: 48 young mature male mice were classified in 4 groups. Control group received only normal saline orally (0.2 ml/day), and the second group was administered MTX ...

[ 2 ] - P-61: Comparing The Protective Effects of Hydro-Alcoholic Extract of Cornus Mas Versus Vitamin E on Methotrexate-Induced Damages on Sperm Parameters

Background: Methotrexate (MTX), as antimetabolite and antifolate compound, is used to treat the certain types of tissue over activity and cancers. The MTX interferes with cell division through inhibiting the purine and pyrimidine synthesis. Moreover, the toxic impact of the MTX on gonadal tissues has been reported. Therefore, current study was designed to evaluate the protective effects of corn...

Co-Authors

Ahmadi A 2