Geravandi SH

[ 1 ] - P-99: The Effects of Zinc in Vitrification Medium on In Vitro Growth of Follicles Derived from Vitrified-Warmed Mouse Ovary

Background: The development of a reliable method for the cryopreservation of mammalian ovary would be an important advancement in the field of reproductive biology for the preservation of genetic resources. The cryopreserved follicles have the potential to develop in-vitro; however, the developmental rate is lower than that of fresh follicles. Researchers have used that of different cryoprotect...

[ 2 ] - P-122: Effects of Cobalt Chloride and Chromium Chloride on Development of Mouse Testes

Background: Cobalt (Co) is an essential trace element for mammals required for the synthesis of vitamin B12. It is not a cumulative toxin but chronic exposure induces negative effects on the organism. It was proven that cobalt passes via placenta appearing in the fetal blood and amniotic fluid and it is shown to possess an embryotoxic effect. Also, chromium (Cr) is recognized as a trace element...

[ 3 ] - P-160: The Effects of Vanadium in Vitrification Medium on In Vitro Growth of Follicles Derived from Vitrified-Warmed Mouse Ovary

Background: Cryopreservation of ovarian tissue is an important option in order to preserve the fertility of cancer patients undergoing chemotherapy and radiotherapy. There are many reports on adding some materials such as calcium, ascorbate and antioxidants to freezing medium. Vanadium is one of the minerals, which is very important as a trace element for normal cell function as well as develop...

[ 4 ] - P-251: Effects of Indomethacin on Postnatal Development of Mouse Testes

Objective: Indomethacin is a non-selective cyclooxygenase (COX) inhibitor that is commonly administered to extremely low gestational age neonates for symptomatic patent ductus arteriosus. It suppresses prostaglandins which modulate growth and secretion of various hormones. We examined the hypothesis that early postnatal administration of Indomethacin may influence growth and development of test...

[ 5 ] - P-254: The Effects of Zinc in Vitrification Medium on In vitro Maturation of Oocytes Derived from Vitrified-Warmed Mouse Ovary

Background: Cryopreservation of ovarian tissue is an important option for preserving the fertility of cancer patients undergoing chemotherapy and radiotherapy. Researchers have used different cryoprotectants and various techniques to improve the cryopreservation of ovaries However, despite significant recent progress, the efficiency of ovary cryopreservation is still low. Zinc is essential for ...

[ 6 ] - P-255: The Effects of Vanadium in Vitrification Medium on in vitro Maturation of Oocytes Derived from Vitrified-Warmed Mouse Ovary

Background: Since the freezing method was offered, much effort has been done to improve the freezing conditions in different studies and the impact of different freezing methods and mediums on oocyte, embryo and ovarian tissues has been examined. Based on studies, minerals play an important role in oocyte maturation and subsequent embryo development. Vanadium is one of the minerals, which is ve...

[ 7 ] - P-96: Mechanical Activation of Parthenogenesis in Mouse Oocytes Using Hydrostatic Pressure

Effective protocols are introduced for parthenogenesis activation in oocytes. Hydrostatic pressure can act as a mechanical stimulator that rearranges egg contents, leading to new structural or molecular combination. Alternatively, mechanical stimulation could stimulate a mechanically-gated process, such as opening or closing of stretch activated ion channels. This study, investigated the use of...

[ 8 ] - P-97: Parthenogenetic Activation of Mouse Oocyte Using Calcium Ionophore in The Presence of Different Concentrations of Extracellular Calcium

Background: Parthenogenetic activation is a possible way to produce homogeneous embryos with the some ploidy. Probably such embryos could be used in other areas of biotechnology. Calcium signals are known as important regulators of oocyte activation. Extracellular calcium is required for initiation of meiotic resumption and development. Calcium ionophore A23187 is known to elevate intracellular...

[ 9 ] - P-217: The Effect of Progesterone on The In Vitro Maturation of Mouse Germinal Vesicle Oocytes Derived from Polycystic Ovary

Background: Polycystic ovary syndrome (PCOS) is characterized by chronic anovulation and hyperandro genism and affects approximately 5-10% of women of reproductive age. In vitro maturation (IVM) of mammalian oocytes has become an efficient method to produce mature oocytes in order to use in assisted reproductive techniques such as in vitro fertilization (IVF), intra cytoplasmic sperm injection ...

[ 10 ] - P-56: The Effect of Hydrostatic Pressure on Mouse Sperm Hyperactivation

Background: Mammalian sperm are not ready to fertilize oocyte immediately after ejaculation. Sperm achieve this ability after undergoing the processes of capacitation and hyperactivation. Hyperactivation refers to a change in the motility pattern of the sperm. Pharmacological reagents and physical-mechanical forces have been used in sperm from a variety of species. Hydrostatic pressure is a cru...

[ 11 ] - P-65: Polycystic Ovary Syndrome Induction in NMRI Mice by Testosterone Enantate

Background: Polycystic ovary syndrome (PCOS) is a heterogeneous disease characterized by hyperandrogenaemia, hirsutism, oligo-or amenorrhea, and anovulation. A common feature of PCOS is the accumulation of small subcortical follicles and increased ovarian stromal volume, causing a characteristic ultrasound image and a basis for the most commonly used designation for the syndrome. In order to th...

[ 12 ] - P-70: The Effect of Hydrostatic Pressure on Parthenogenetic Activation of Mouse Oocytes Derived from In vitro Grown Ovarian Follicles

Background: Parthenogenesis is the production of an embryo from a female gamete in the absence of any contribution from a male gamete, with or without the eventual development into an adult. In vivo, mammalian parthenogenesis is a rare event. Parthenogenesis can be efficiently induced in vitro with a variety of mechanical, chemical, and electrical stimuli in several species. Hydrostatic pressur...