Salman Yazdi R

[ 1 ] - P-27: The Effect of Varicocelectomy onThe Serum Testosterone Level in Infertile Men with Grade (II - III) Varicocele

Background: To determine whether men with varicoceles have lower testosterone levels than those without and to ascertain if testosterone levels increase after varicocelectomy and or to determine whether the varicocele grade is related to the degree of improvement in serum testosterone levels after varicocelectomy and also older age is associated with improvements in testosterone after varicocel...

[ 2 ] - P-238: Lack of Association of Estrogen Receptor Polymorphisms with Male Infertility

Background: Estrogen is recognized as one of the significant regulator of spermatogenesis. Estrogens are synthesized in the male reproductive system (sertoli and leydig cells). Estrogen function is mediated by estrogen receptors (ER-α or ER-β). Some studies have suggested an association between single nucleotide polymorphisms (SNPs) rs2234693 (ESR1 pvuII C>T), rs1801132 (ESR1 325 C->G) of ERα g...

[ 3 ] - I-5: Semen Analysis - Clinical Laboratories; Is Standardization Applied?

Reduced semen quality is commonly claimed to be one of the main signs of male infertility and thus, analysis of semen is recommended as the cornerstone of a male fertility investigation. However, to control possible sources of physiological and methodological variation, and to generate reliable information on semen quality that can be accurately compared across different laboratories, semen ana...

[ 4 ] - O-5: Endocrinological and Morphological Evaluation of Vitrified-Warmed Ovarian Tissue

Background: Our aim was to evaluate the recovery rate of ovarian function and the activity of hypothalamus-hypophiseal- gonadal axis following transplantation of vitrified ovaries. Materials and Methods: Five weeks-old female Wistar Rats were distributed randomly in two experimental groups; Fresh Transplanted, Vitrified-Transplanted and 8 weeks-old female Wistar rats were considered as control ...

[ 5 ] - O-15: Different Leukocyte Concentrations in Normal and Abnormal Human Semen and Its Correlation with Sperm Intracellular Reactive Oxygen Species, Lipid Peroxidation and DNA Fragmentation

Background: According to World Health Organization guideline (WHO 2010), seminal leukocyte concentration over 1×106/mL is a threat for sperm quality because of their role in reactive oxygen species (ROS) production, lipid per-oxidation (LPO) and later DNA fragmentation (DF). However, this threshold is equal for all semen samples without attention to their qualities. Therefore this study was set...

[ 6 ] - P-41: Association Study of MICA*008 Gene Polymorphism with Chlamydia Trachomatis Infection in Infertile Men Reffer to Royan Institute

Background: Chlamydia trachomatis(CT) is an obligate intracellular bacteria, requires living cells to replicate itself. CT infection can remain up to 4 years in the couple and affect their fertility. The relationship between CT and infertility is very important because most patients are asymptomatic and untreated. After infection with CT, NK activation signals begin through interactions of its ...

[ 7 ] - P-162: Pathophysiology of Endometriosis is Interacted by MIF, its Receptor and COX-2

Background: Endometriosis is a gynecological disease associated with severe pelvic pain and infertility. Immunological changes that occur in patients with endometriosis include reduced natural killer cell and T-lymphocyte cytotoxicity in the peritoneal fluid, and an elevated number of activated macrophages. MIF via its receptor, CD74, initiates a signaling cascade that leads to proliferation an...

[ 8 ] - P-193: Chlamydia Trachomatis Can Increase Sperm DNA Fragmentation in Infertile Men

Background: Chlamydia Trachomatis (CT) is an obligate intracellular bacteria, that requires living cells to replicate itself and is responsible for lower urinary tract disease in men and women. It can cause urethritis, epididymitis, orchitis and complications such as chronic prostatitis in men. Chlamydia infections may also directly affect male fertility by damaging the sperm, because sperm par...

[ 9 ] - I-4: External Quality Assessment - A Necessity in The Andrology Laboratory

Andrology laboratories need to produce reliable results for appropriate diagnostic and health care decisions. Since semen analysis is highly complex and procedurally difficult to standardize, quality control (QC) is essential to detect and correct systematic errors and high variability of results. The large discrepancies between assessments of sperm concentration and morphology in different lab...

[ 10 ] - P-194: SEPT12-G800A Polymorphism in Azoospermic Infertile Men Referred to Royan Institute

Background: SEPTINS belong to a family of polymerizing GTP-binding proteins that are required for many cellular functions, such as vesicular trafficking, mitosis, membrane compartmentalization and cytoskeletal remodeling. Among all SEPTIN genes, SEPT12 is dominantly expressed in testis tissue of adults, known as an essential annulus component of mature sperm. Therefore, it is hypothesized that ...

[ 11 ] - P-16: The Correlation between Sexual Practices and the Development of Antisperm Antibodies

Background: Infertility is one of the most common and important subjects in today’s obstetrics and gynecology. Immunological factors such as the presence of antisperm antibodies (ASA) are challenging etiologies for infertility. This study was performed to determine the correlation between the type of sexual practices (oral‚ anal and vaginal during menstruation) and the ASA levels in semen and i...