Saghar Salehpour

[ 2 ] - I-36: The Role of LH in Controlled Ovarian Stimulation

It is known that the follicular selection and final stages of follicular maturation are equal if not more dependent on low circulating levels of LH.In addition to stimulating production of thecal androgens as substrate for estrogen synthesis, LH stimulates granulose cell via LH receptors induced by FSH and estrogen in larger but not smaller follicles. The data from numerous assisted reproductio...

[ 3 ] - P-220: A Two Purpose Use of Orlistat in Obese Women with Polycystic Ovary Syndrome: Weight Loss and Androgen Reduction

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in young women. PCOS affects 6% and 8% of women in reproductive age. Hyperandrogenism is the hallmark of PCOS. Clinically, it is possible to observe hirsutism, acne, androgenic alopecia, and signs of virilization. Laboratory examination reveals increased androgen levels. Excessive androgen has an important r...

[ 4 ] - I-31: New Treatment in PCOS

as an important metabolic as well as reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected women have marked insulin resistance, independent of obesity. Prolonged (6 months) medical therapy for hirsutism is necessary to document effectiveness . Many drugs used for the treatment of hirsutism are not FDA approved for this indication. No effective treatment fo...

[ 6 ] - I-37: Pathogenesis of PCOS and N AcetyCysteine, A Novel Remedy for Poly Cystic Ovarian Syndrome

Background: Poly cystic ovarian syndrome (PCOS) is the most prevalent endocrinopathy among women and the most common underlying diagnosis for anovulatory infertility. The role of insulin-resistance (IR) and hyperinsulinemia in pathophysiology and clinical manifestations of the syndrome depicts the importance of evaluation of the efficacy of insulin reducing medications. N acetyl cysteine (NAC) ...

[ 7 ] - I-47: ART Outcome in PCOS Patients

PCOS is still a problem in gynecology and infertility. Especially in ART the problem of PCOS patients is bigger and more highlighted. These patients are prone to over and under stimulation. Strategies to overcome hyper stimulation are: use of metformin, ovarian drilling, use of minimal stimulation, suppressing LH with use of OCP or GnRh analogues, use of GnRh antagonist in COH. But none of thes...

[ 8 ] - Leptin, Ghrelin, Adiponectin, Homocysteine and Insulin Resistance Related to Polycystic Ovary Syndrome

The relationship between leptin, adiponectin, ghrelin, homocysteine, insulin resistance and other biochemical factors in women with polycystic ovary syndrome (PCOS) is controversial. We review how the expanded role of these factors in reproduction might impact our understanding of PCOS. For purposes of our review, we accessed the PUBMED database during the past 10 years. Our review confirms tha...

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