Mahnaz Ashrafi

Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

[ 1 ] - The Effects of Maternal and Paternal Body Mass Index on Live Birth Rate after Intracytoplasmic Sperm Injection Cycles

Objective The present study was designed to evaluate the effect of couple`s obesity simultaneously on in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes. MaterialsAndMethods This cross-sectional study was performed in Royan institute between January 2013 and January 2014. The recorded data of all patients during this time period were evaluated. The study population was ...

[ 2 ] - Congenital Malformations in Singleton Infants Conceived by Assisted Reproductive Technologies and Singleton Infants by Natural Conception in Tehran, Iran

Objective Multiple pregnancies occur more frequently in assisted reproductive technology (ART) compared to normal conception (NC). It is known that the risk of congenital malformations in a multiple pregnancy are higher than single pregnancy. The aim of this study is to compare congenital malformations in singleton infants conceived by ART to singleton infants conceived naturally. MaterialsAndM...

[ 3 ] - Evaluation of Risk Factors Associated with Endometriosis in Infertile Women

Objective Endometriosis affects women’s physical and mental wellbeing. Symptoms include dyspareunia, dysmenorrhea, pelvic pain, and infertility. The purpose of this study is to assess the correlation between some relevant factors and symptoms and risk of an endometriosis diagnosis in infertile women. MaterialsAndMethods A retrospective study of 1282 surgical patients in an infertility Institute...

[ 4 ] - Frequency of Hearing Defect and Ear Abnormalities in Newborns Conceived by Assisted Reproductive Techniques in Royan Institute

Background Assisted reproductive techniques (ART) are used with increasing frequency worldwide. The present research was conducted to determine the effects of ART on hearing defects and ear abnormalities. MaterialsAndMethods n a descriptive, cross-sectional, non-randomized study, the status of hearing and ear abnormalities was assessed in 300 newborns conceived by ART at Royan Institute, Tehran...

[ 5 ] - The Presence of Anti Thyroid and Anti Ovarian Auto-Antibodies in Familial Premature Ovarian Failure

Background Premature ovarian failure (POF) is a disorder of multi causal etiology. Autoimmunity has been proposed as a mechanism for some cases of ovarian follicle dysfunction which is evident in POF. The aim of this study was to identify the level of auto-antibodies in POF and familial POF patients. MaterialsAndMethods In this study, auto-antibodies including anti-ovarian antibody (AOA), anti ...

[ 6 ] - Anti-Thyroid Peroxidase and Risk of Recurrent Spontaneous Abortion

Background Approximately 2-4% of all women have recurrent spontaneous abortion (RSA); however, the cause is determined in only 50% of cases. Recent studies have shown an association between thyroid autoantibodies as a sign of thyroid autoimmunity and abortion. The aim of the present study was to determine whether circulating anti-thyroid peroxidase (anti-TPO) was associated with RSA. MaterialsA...

[ 7 ] - 0ocyte Related Factors and Chance of Implantation

Background Endometriosis has been widely implicated as one of the causes of chronic pelvic pain, dysmenorrhea and infertility. The purpose of our study was to define the presumed correlation between visual and histologic diagnostic features of endometriosis based on the peritoneal findings identified in laparoscopy as a diagnostic trial with a standardized technique. So, all the specimens inclu...

[ 8 ] - The Pregnancy Outcomes of Day 2 versus Day 3 Embryo Transfer: A Cross-Sectional Study

Background The objective was to evaluate whether extending the embryo culture period from 2 to 3 days would yield a more optimal selection of viable embryos, thereby increasing the pregnancy rat. MaterialsAndMethods We have retrospectively analyzed pregnancy rates in the patients who had embryo transfer either on day 2 (582 patients) or on day 3 (387 patients) post-insemination over a 10-month ...