Roshanak Aboutorabi
[ 1 ] - Impact of Metformin and Pioglitazone on Serum Level of Tumor Necrosis Factor-Alpha and Lipid Profiles during Implantation Window in Diabetic Rats
Objective Objectives: The present study was designed to evaluate the serum lipid profile and Tumor Necrosis Factor alpha (TNF-ɑ) level in diabetic rats at the time of implantation. Type 2 diabetes mellitus (T2DM) could affect various systems, including innate immune system and causes chronic low-grade inflammation which increases the level of TNF-ɑ. Furthermore, T2DM is often accompanied by imp...
[ 2 ] - Evaluation of Osteopontin Gene Expression in Endometrium of Diabetic Rat Models Treated with Metformin and Pioglitazone
Objective Osteopontin (Opn) is one of the co-factors which participates in cell adhesion and invasion during implantation process. Increased incidence of spontaneous abortion is reported in diabetic women. Several reports have shown Opn gene expression changes in diabetic condition in several tissues. Therefore, this study was designed to evaluate the effects of diabetes on Opn gene expression ...
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