Ioannis D. Karantas
Hippokration General Hospital, 2nd Clinic of Internal Medicine, Thessaloniki, Greece.
[ 1 ] - Polymeric Microparticles as Alternative Carriers for Antidiabetic Glibenclamide Drug
Background: Glibenclamide is a lipophilic drug widely used in type 2 diabetes treatment. However, its low bioavailability limits its use. Thus, novel formulations should be applied to improve the drug’s bioavailability. Objectives: This study aimed to develop alternative carriers for oral delivery of glibenclamide. For this purpose, two biocompatible polymers, poly(e-caprolactone) and poly(but...